Fortfahren mit
C7374
CK-636
≥98% (HPLC)
Synonym(e):
CK-0944636; N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 5 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 95.90 CHF 81.51 |
Über diesen Artikel
Empirische Formel (Hill-System):
C16H16N2OS
CAS-Nummer:
Molekulargewicht:
284.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
CHF 81.51
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Unterstützung erhaltenQuality Level
assay
≥98% (HPLC)
form
powder
color
peach to light pink
solubility
DMSO: ≥20 mg/mL
storage temp.
2-8°C
SMILES string
Cc1[nH]c2ccccc2c1CCNC(=O)c3cccs3
InChI
1S/C16H16N2OS/c1-11-12(13-5-2-3-6-14(13)18-11)8-9-17-16(19)15-7-4-10-20-15/h2-7,10,18H,8-9H2,1H3,(H,17,19)
InChI key
ACAKNPKRLPMONU-UHFFFAOYSA-N
Biochem/physiol Actions
CK-636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation. CK-636 inserts into the hydrophobic core of Arp3 and alters its conformation. Both classes of compounds inhibit formation of actin filament comet tails by Listeria and podosomes by monocytes.
CK-636 inhibits the activity of actin-related protein (Arp)2/3 complex; binds between Arp2 and Arp3, blocks movement of Arp2 and Arp3 into active conformations, inhibits ability to nucleate actin filaments.
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Dieser Artikel | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: ≥20 mg/mL | solubility DMSO: ≥25 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility DMSO: >5 mg/mL |
| color peach to light pink | color white to tan | color white to beige | color white to beige |
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| C7374-25MG | 04061833218099 |
| C7374-5MG | 04061833218105 |