SML0006

CK-666

≥98% (HPLC), powder, Arp2/3 comple inhibitor

• Synonym(e): 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide, CK 666, CK-0944666
• Empirische Formel (Hill-System): C₁₈H₁₇FN₂O
• CAS-Nummer: 442633-00-3
• Molekulargewicht: 296.34
• MDL-Nummer: MFCD03036271
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825083
• NACRES: NA.77

Eigenschaften

• Produktbezeichnung: CK-666, ≥98% (HPLC), powder
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to tan
• Löslichkeit: DMSO: ≥25 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: Cc1[nH]c2ccccc2c1CCNC(=O)c3ccccc3F
• InChI: 1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22)
• InChIKey: UXRKUKRXVWJFER-UHFFFAOYSA-N

Beschreibung

Anwendung

CK-666 may be used to study Arp2/3-mediated structural changes in cells.

Biochem./physiol. Wirkung

CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents its movement into active conformation.[1]

CK-666 is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable