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C6277

Kongorot

Dye content, ≥85%, certified by the Biological Stain Commission, powder

Synonym(e):

Direktrot 28, Kongorot 4B

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Ihnen/SKUVerfügbarkeitPreis
25 g
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CHF 421.00

Über diesen Artikel

Empirische Formel (Hill-System):
C32H22N6Na2O6S2
CAS-Nummer:
Molekulargewicht:
696.66
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
209-358-4
MDL number:
Colour Index Number:
22120
Beilstein/REAXYS Number:
3894858

CHF 421.00


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Produktname

Kongorot, certified by the BSC, BioXtra

agency

certified by the BSC

Quality Segment

product line

BioXtra

form

powder

composition

Dye content, ≥85%

technique(s)

microbe id | staining: suitable

mp

>360 °C (lit.)

solubility

H2O: 10 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;

InChI key

IQFVPQOLBLOTPF-HKXUKFGYSA-L

Application

Kongorot wird für die Färbung von β-Amyloid-Peptiden verwendet.
Zertifiziert für den Einsatz als Gegenfärbung für Alaun basiertes Hämatoxylin und in der Highman- oder Churukian-Modifikation der Amyloid-Färbung nach Puchtler.

Biochem/physiol Actions

Kongorot ist ein Benzidin-basierter anionischer Diazofarbstoff. Es handelt sich hierbei um einen histologischen Farbstoff, der an viele Amyloidproteine bindet und für die Quantifizierung der Amyloid-β-Peptid-Aggregation verwendet wird. Kongorot interagiert mit β-D-Glucanen, Polysacchariden, die durchgängig β-(1→4)-gebundene D-Glucopyranosyl-Einheiten sowie einige Hemicellulose-Galactoglucomannane enthalten.

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Dieser Artikel
C6767S4261S4136
technique(s)

microbe id | staining: suitable

technique(s)

titration: suitable

technique(s)

-

technique(s)

-

form

powder

form

powder

form

powder

form

powder

solubility

H2O: 10 mg/mL

solubility

H2O: 1 mg/mL

solubility

-

solubility

toluene: 1 mg/mL, clear, red

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

composition

Dye content, ≥85%

composition

Dye content, ≥35%

composition

Dye content, ≥80%

composition

Dye content, ≥80%


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pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 1B - Repr. 2

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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Questions

1–3 of 3 Questions  
  1. looking for Congo Red stain, the one used in histopathology, but not sure which of the options is the best.

    1 answer
    1. The dry powder form allows for the preparation of Congo Red for various uses. The recommended dry dye for ordering is C6277 is currently undergoing BSC certification. Congo Red is a dye used for various staining procedures, mostly for staining of amyloid.

      Helpful?

  2. Why does the SDS for Congo Red list carcinogen as an OSHA hazard, (Section 2) but in Section 11 on carcinogenicity, it states that there is no component identified as a carcinogen?

    1 answer
    1. The reason that there is not an OSHA listing for carcinogens on most of SDS that have a hazard of a carcinogen hazard is because that section of the SDS is specifically for the OSHA regulated carcinogens, also referred to as the OSHA 13. Congo red at this time is not specifically called out  as a carcinogen by the other 3 Organizations listed (IARC, NTP, ACGIH) either. Congo red is listed by the European Classification Labeling & Packaging (CLP) Regulation (which is a pretty definitive guide for hazard classification), as a carcinogen. No other organizations have had the time to classify this material at this time. This is why it is only listed as a carcinogen in section 2 and in section 15.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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