Fortfahren mit
A0664
4-Aminobutylphosphonic acid
≥99%
Synonym(e):
P-(4-aminobutyl)-phosphonic acid
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
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Über diesen Artikel
Empirische Formel (Hill-System):
C4H12NO3P
CAS-Nummer:
Molekulargewicht:
153.12
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenQuality Level
assay
≥99%
form
powder
color
white
application(s)
detection
SMILES string
NCCCCP(O)(O)=O
InChI
1S/C4H12NO3P/c5-3-1-2-4-9(6,7)8/h1-5H2,(H2,6,7,8)
InChI key
IDPXFPYGZRMMKZ-UHFFFAOYSA-N
Biochem/physiol Actions
4-Aminobutylphosphonic acid, a GABA B receptor ligand, is used in studies on the regulation of prolactin (PRL) secretion and differential GABA receptor research.
4-aminobutylphosphonic acid, the phosphonic acid analogue of delta-aminovaleric acid, inhibits gamma-aminobutyric acid B (GABA-B receptor) binding without influencing either isoproterenol- or forskolin-stimulated cyclic AMP production.
Other Notes
Analog of δ-aminovaleric acid
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| form powder | form crystals | form powder | form powder |
| assay ≥99% | assay 98% | assay ≥98% (HPLC) | assay ≥97% (NMR) |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| color white | color - | color - | color white to beige |
| application(s) detection | application(s) - | application(s) - | application(s) - |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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The activity of many endocrine cells is regulated by gamma-aminobutyric acid (GABA). The effects of GABA are mediated by GABAA and/or GABAB receptors. While GABAB receptors in the central nervous system have now been extensively characterized, little is known of
L S Wong et al.
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The application of 1.2 and 12.0 micrograms/side of the GABAA receptor agonist 3-aminopropane sulphonic acid bilaterally into the nucleus accumbens (Acb) of rats nonsignificantly depressed locomotor activity as assessed in automated Animex activity cages, while the highest dose (60 micrograms/side)
J Ong et al.
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The effects of five phosphonic derivatives of GABA on the release of [3H]-GABA from rat neocortical slices, preloaded with [3H]-GABA, were investigated. Phaclofen and 4-aminobutylphosphonic acid (4-ABPA) increased the overflow of [3H] evoked by electrical stimulation (2 Hz) in a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A0664-250MG | 04061832414560 |