39286

Hydroxystilbamidin-bis(methansulfonat)

suitable for fluorescence, ≥96.0% (HPLC)

• Synonym(e): 2-Hydroxy-stilben-4,4′-dicarbamidin-bis-(methansulfonat), Fluoro-Gold^™
• Empirische Formel (Hill-System): C₁₈H₂₄N₄O₇S₂
• CAS-Nummer: 223769-64-0
• Molekulargewicht: 472.54
• MDL-Nummer: MFCD01863083
• UNSPSC-Code: 41116100
• PubChem Substanz-ID: 57649893
• NACRES: NA.32

Eigenschaften

• Assay: ≥96.0% (HPLC)
• Form: powder
• Fluoreszenz: λ_ex 318 nm; λ_em 560 nm in TBE Buffer
• Eignung: suitable for fluorescence
• Lagertemp.: 2-8°C
• SMILES String: CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N
• InChI: 1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
• InChIKey: YGNSQKCULHSJDC-HFPMQDOPSA-N

Beschreibung

Allgemeine Beschreibung

Hydroxystilbamidine bis (methanesulfonate), also known as Fluoro-Gold, is a retrograde fluorescent tracer. Chemically, Hydroxystilbamidine is a weak base and can cross cell membranes in its uncharged form.

A few properties of Hydroxystilbamidine bis (methanesulfonate) are:

• Intense Fluorescence.
• Extensive filling of dendrites.
• High Resistance to fading.
• No uptake by undamaged fibers.
• No diffusion from labelled cells.
• Highly compatible with other neuro-histochemical techniques.

Anwendung

Hydroxystilbamidine bis(methanesulfonate), a fluorescent retrograde tracer (axonal transport), is used for neural mapping in microanatomical research.

Hydroxystilbamidine bis (methanesulfonate) or Fluoro-Gold (FG) is used to label neurons and investigate the early effects of hearing loss. It is used to study morphological features of extensive axonal projections within the CNS by labelling the cells.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves