1597005

Chininsulfat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Chinin -hemisulfat (Salz) Monohydrat, Chinin-sulfat (2:1) (Salz) Dihydrat
• Empirische Formel (Hill-System): C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• CAS-Nummer: 207671-44-1
• Molekulargewicht: 391.47
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751013
• MDL number: MFCD00150790
• Beilstein/REAXYS Number: 6113937

Eigenschaften

• grade: pharmaceutical primary standard
• API family: quinine
• mol wt: monograph mol wt. 782.94
• manufacturer/tradename: USP
• mp: ~225 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
• InChI key: ZHNFLHYOFXQIOW-LPYZJUEESA-N

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Quinine sulfate is the sulfate salt of quinine, an alkaloid, obtained from the bark of Cinchona species.

(C₂₀H₂₄N₂O₂)₂ . H₂SO₄ . 2H₂O

Application

Quinine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Quinine Sulfate Capsules
• Quinine Sulfate Tablets

Biochem/physiol Actions

blockiert Kaliumkanäle. Anti-Malaria

blockiert Kaliumkanäle. Anti-Malaria, anticholinerges, antihypertensives und hypoglykemisches Agens; ursprünglich aus südafrikanischen Bäumen der Gattung Cinchona isoliert.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338