1076352

Bretyliumtosylat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): (o-Brombenzyl)-ethyldimethylammonium-p-toluolsulfonat
• Empirische Formel (Hill-System): C₁₈H₂₄BrNO₃S
• CAS-Nummer: 61-75-6
• Molekulargewicht: 414.36
• NACRES: NA.24
• PubChem Substance ID: 329749129
• UNSPSC Code: 41116107
• MDL number: MFCD00038731

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: bretylium
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.CC[N+](C)(C)Cc2ccccc2Br
• InChI: 1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChI key: KVWNWTZZBKCOPM-UHFFFAOYSA-M
• Gene Information: human ... SLC6A2(6530)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bretylium tosylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Bretylium Tosylate Injection
• Bretylium Tosylate in Dextrose Injection

Biochem/physiol Actions

Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade; class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase.

Class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable