P0928

O⁷-Pentylresorufin

≥98% (TLC), Fluorimetric Cytochrome P450 substrate, powder

• Synonym(e): 7-Pentyloxy-3H-phenoxazin-3-on, Pentoxyresorufin
• Empirische Formel (Hill-System): C₁₇H₁₇NO₃
• CAS-Nummer: 87687-03-4
• Molekulargewicht: 283.32
• NACRES: NA.47
• PubChem Substance ID: 24898138
• UNSPSC Code: 12161501
• MDL number: MFCD00037664
• Beilstein/REAXYS Number: 8394939

Eigenschaften

• Produktname: O⁷-Pentylresorufin,
• assay: ≥98% (TLC)
• Quality Segment: 200
• form: powder
• solubility: acetonitrile: 0.95- 1.05 mg/mL, clear, orange
• storage temp.: 2-8°C
• SMILES string: CCCCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1
• InChI: 1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3
• InChI key: ZPSOKQFFOYYPKC-UHFFFAOYSA-N

Beschreibung

General description

Resorufin pentyl ether is an analog of resazurin. Resorufin is a redox probe which is colorless and non-fluorescent in its reduced state. On oxidation, it fluoresces red. Resorufin is used widely as an indicator in microbiological media. It can be used to differentiate between actively metabolizing cells and inactive or dead cells.

Application

Resorufin pentyl ether has been used as a substrate to study the effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.

Biochem/physiol Actions

Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves