D5520

Dimethyl-dicarbonat

for histidine methylation

• Synonym(e): DMPC, Dimethyl-pyrocarbonat, Pyrokohlensäure-dimethylester
• Lineare Formel: (CH₃OCO)₂O
• CAS-Nummer: 4525-33-1
• Molekulargewicht: 134.09
• EC Number: 224-859-8
• UNSPSC Code: 12352202
• PubChem Substance ID: 24893938
• Beilstein/REAXYS Number: 956715
• MDL number: MFCD00008419

Eigenschaften

• biological source: synthetic
• form: liquid
• refractive index: n20/D 1.392 (lit.)
• bp: 45-46 °C/5 mmHg (lit.)
• density: 1.25 g/mL at 25 °C (lit.)
• storage temp.: room temp
• SMILES string: COC(=O)OC(=O)OC
• InChI: 1S/C4H6O5/c1-7-3(5)9-4(6)8-2/h1-2H3
• InChI key: GZDFHIJNHHMENY-UHFFFAOYSA-N

Beschreibung

Application

Methylates one or two histidine residues at the active site of PEP carboxykinase; the resulting inhibition is only partially reversible.[1]

Methylates one or two histidine residues at the active site of PEP carboxykinase; the resulting inhibition is only partially reversible.[1]

Sicherheitshinweise

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H302,H314,H330
• pcodes: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: 185.0 °F
• flash_point_c: 85 °C
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter