This product is not tested for inducing an animal model of androgenic alopecia. Determination of suitability must be conducted experimentally.
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Über diesen Artikel
Produktname
5α-Androstan-17β-ol-3-on, ≥97.5%
biological source
synthetic
Quality Segment
sterility
non-sterile
assay
≥97.5%
form
powder
drug control
USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility
ethanol: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
SMILES string
[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2
InChI
1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1
InChI key
NVKAWKQGWWIWPM-ABEVXSGRSA-N
Gene Information
human ... AR(367), ESR1(2099), PGR(5241), SERPINA6(866), SHBG(6462)
mouse ... Esr1(13982)
rat ... Ar(24208), Esr1(24890), Nr3c1(24413), Nr3c2(25672), Pgr(25154)
Application
Biochem/physiol Actions
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Repr. 1A
Lagerklasse
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Verwandter Inhalt
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A8380-1G | 04061826652121 |
| A8380-10G | 04061832866482 |
| A8380-5G | 04061832269092 |
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Is this product suitable for inducing an animal model of androgenic alopecia?
1 answer-
Helpful?
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Is it suitable to treat this in cell culture? I've already seen such recommendations.. However, the fact that it is not sterilized is a bit concerning. would it still be possible?
1 answer-
This product has not been tested for suitability in cell culture. While the powder is not sterile, prepared stock solutions may be filter sterilized. The material is soluble at 50 mg/mL in ethanol and may be further diluted using buffer or medium. The peer-reviewed papers listed on this page reference publications the have listed this product used in a number of applications successfully. There are several in vitro and in vivo applications cited. Please see the link below to review one example publication:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099410Helpful?
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