The solubility is not tested internally, but literature indicates solubility in aqueous solution up to about 20 g/L. Solution stability information is not available. It would be best to prepare solutions just prior to use, unless a stability study can be performed by the end user.
Fortfahren mit
79849
(±)-Mevalonsäure-5-phosphat Lithiumsalz Hydrat
95% (TLC)
Synonym(e):
(±)-MVAP-Li, rac-5-Phosphomevalonate lithium salt
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 10 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 224.00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C6H13O7P · xLi+ · yH2O
Molekulargewicht:
228.14 (free acid basis)
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
Technischer Dienst
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Unterstützung erhaltenQuality Level
assay
95% (TLC)
form
powder or crystals
relevant disease(s)
Alzheimer′s disease; autoimmune diseases
storage temp.
2-8°C
SMILES string
OC(CC(C)(O)CCOP(O)(O)=O)=O.[H]O[H].[Li+]
InChI
1S/C6H13O7P.3Li.H2O/c1-6(9,4-5(7)8)2-3-13-14(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H2,10,11,12);;;;1H2/q;3*+1;/p-3
InChI key
VYTYNAKRCDFACM-UHFFFAOYSA-K
Biochem/physiol Actions
Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| assay 95% (TLC) | assay ≥95% (TLC) | assay ≥96.0% (GC) | assay ≥95.0% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder or crystals | form powder | form - | form powder or crystals |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C |
| relevant disease(s) Alzheimer′s disease; autoimmune diseases | relevant disease(s) - | relevant disease(s) - | relevant disease(s) - |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Li Gong et al.
Cell death & disease, 10(4), 327-327 (2019-04-13)
The mevalonate pathway is known for the synthesis of cholesterol, but recent studies have reported that it also controls Hippo signaling, which is critical for the regulation of organ size and tumorigenesis. Here, we discover that the suppression of the
D N Skilleter et al.
The Biochemical journal, 124(2), 407-417 (1971-09-01)
1. Phosphomevalonate kinase and 5-pyrophosphomevalonate decarboxylase have been purified from the freeze-dried latex serum of the commercial rubber tree Hevea brasiliensis. 2. The phosphomevalonate kinase was acid- and heat-labile and required the presence of a thiol to maintain activity. 3.
Inhibition of hepatic cholesterol biosynthesis by 3,5-dihydroxy-3,4,4-trimethylvaleric acid and its site of action.
F H Hulcher
Archives of biochemistry and biophysics, 146(2), 422-427 (1971-10-01)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C2175-.5MG | 04061832676302 |
| C2175-1MG | 04061833475270 |
| C2175-5MG | 04061832676326 |
| C2175-250UG | 04061832676319 |
| 79849-50MG | 04061832966588 |
| 79849-10MG | 04061832386027 |
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PBSなどの水溶液に溶かせますか？その時は、水溶液を冷凍保存できますか？どのくらいの期間保存できますか？
1 answer-
Helpful?
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