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46393

Sigma-Aldrich

Fluo-3

suitable for fluorescence, ~70%

Synonym(e):

4-(2,7-Dichlor-6-hydroxy-3-oxo-9-xanthenyl)-4′-methyl-2,2′-(ethylendioxy)-dianilin-N,N,N′,N′-tetraessigsäure

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About This Item

Empirische Formel (Hill-System):
C36H30Cl2N2O13
CAS-Nummer:
123632-39-3
Molekulargewicht:
769.54
MDL-Nummer:
MFCD00083337
UNSPSC-Code:
12352106
PubChem Substanz-ID:
329757162
NACRES:
NA.32

Assay

~70%

Form

solid

Löslichkeit

H2O: soluble

Fluoreszenz

λex 506 nm; λem 526 nm in 0.1 M Tris pH 8.0, esterase 30 mM Ca2+

Eignung

suitable for fluorescence

Lagertemp.

−20°C

SMILES String

Cc1ccc(N(CC(O)=O)CC(O)=O)c(OCCOc2cc(ccc2N(CC(O)=O)CC(O)=O)C3=C4C=C(Cl)C(=O)C=C4Oc5cc(O)c(Cl)cc35)c1

InChI

1S/C36H30Cl2N2O13/c1-18-2-4-24(39(14-32(43)44)15-33(45)46)30(8-18)51-6-7-52-31-9-19(3-5-25(31)40(16-34(47)48)17-35(49)50)36-20-10-22(37)26(41)12-28(20)53-29-13-27(42)23(38)11-21(29)36/h2-5,8-13,41H,6-7,14-17H2,1H3,(H,43,44)(H,45,46)(H,47,48)(H,49,50)

InChIKey

OZLGRUXZXMRXGP-UHFFFAOYSA-N

Anwendung

Fluo-3 and related molecule Fluo3/AM are used as a fluorescence indicator of intracellular calcium (Ca2+). Fluo-3 may be use for flow cytometry and confocal laser scanning microscopy using visible light excitation (compatible with argon laser sources operating at 488 nm). Fluorescence intensity increases about 40-fold after calcium binding.

Sonstige Hinweise

Fluoreszenzindikator für Calcium mit Anwendung in der Durchflusszytometrie. Die Fluoreszenzintensität steigt circa um den Faktor 40 nach Bindung an Calcium

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

14510

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