D6003

Digoxin

analytical standard

• Synonym(e): 12β-Hydroxydigitoxin
• Empirische Formel (Hill-System): C₄₁H₆₄O₁₄
• CAS-Nummer: 20830-75-5
• Molekulargewicht: 780.94
• Beilstein: 77011
• EG-Nummer: 244-068-1
• MDL-Nummer: MFCD00003674
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329798818
• NACRES: NA.24

Eigenschaften

• Biologische Quelle: plant (Digitalis lanata)
• Qualitätsniveau: 100
• Qualität: analytical standard
• Assay: ≥95.0% (HPLC)
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Löslichkeit: methanol: methylene chloride (1:1): 0.5%, clear, colorless
• Anwendung(en): food and beverages; forensics and toxicology; veterinary
• Format: neat
• Funktionelle Gruppe: ketone
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4
• InChI: 1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
• InChIKey: LTMHDMANZUZIPE-PUGKRICDSA-N
• Angaben zum Gen: human ... ATP1A1(476) , ATP1A2(477) , ATP1A3(478) , ATP1A4(480) , ATP1B1(481) , ATP1B2(482) , ATP1B3(483) , FXYD2(486)

Beschreibung

Anwendung

Digoxin may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Ein kardiales Glykosid, Substrat für Pgp, reguliert Pgp Expression nach oben und SXR (Steroid Xenobiotic Receptor) nach unten.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H300,H331,H373
• P-Sätze: P260 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P314
• Gefahreneinstufungen: Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges