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1491300

USP

Oxytocin

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

α-Hypophamin, Ocytocin

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Über diesen Artikel

Empirische Formel (Hill-System):
C43H66N12O12S2
CAS-Nummer:
Molekulargewicht:
1007.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3586108
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grade

pharmaceutical primary standard

agency

USP

API family

oxytocin

form

powder

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

SMILES string

[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)[C@@H](C)CC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O

InChI

1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1

InChI key

XNOPRXBHLZRZKH-DSZYJQQASA-N

Gene Information

human ... OXTR(5021)

General description

Oxytocin is a nonapeptide hormone produced in the hypothalamus and secreted by the posterior pituitary. It stimulates uterine contractions and lactation. The USP reference standard enables bioassay validation, potency testing, and structural identity confirmation in oxytocin products.

The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Oxytocin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Oxytocin Injection

Biochem/physiol Actions

Stimuliert Uteruskontraktion und Milchbildung; erhöht die Na+-Ausscheidung; stimuliert myometriale GTPase und Phospholipase  C.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.
This product is part of the USP Biologics program.

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Dieser Artikel
O0700000ABN297O3251
Oxytocin United States Pharmacopeia (USP) Reference Standard

USP

1491300

Oxytocin

Oxytocin European Pharmacopoeia (EP) Reference Standard

O0700000

Oxytocin

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

grade

-

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

application(s)

USP Biologics
pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

form

powder

form

-

form

-

form

lyophilized powder

format

neat

format

neat

format

-

format

-

API family

oxytocin

API family

oxytocin

API family

-

API family

-


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Lagerklasse

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Oxytocin
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(3), 3366-3366 (2013)
Y Aoki et al.
Molecular psychiatry, 20(4), 447-453 (2014-07-30)
The neuropeptide oxytocin may be an effective therapeutic strategy for the currently untreatable social and communication deficits associated with autism. Our recent paper reported that oxytocin mitigated autistic behavioral deficits through the restoration of activity in the ventromedial prefrontal cortex
Elliot C Brown et al.
Psychiatry research, 219(3), 436-442 (2014-07-23)
Patients with schizophrenia suffer from dysfunctional social behaviour. Social approach and avoidance (AA) has been associated with motor responses, as the affective valence and gaze direction of facial stimuli can bias push and pull motor tendencies. The aim of this



Global Trade Item Number

SKUGTIN
1491300-1VL04061838626110

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