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T1001
Thyroglobulin aus Rinderschilddrüse
powder, ≥90% (agarose gel electrophoresis)
Synonym(e):
Globulins thyro, Thyractin
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 100 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 212.00 | |
| 500 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 828.00 | |
| 1 g | Warenkorb auf Verfügbarkeit prüfen | CHF 1’080.00 | |
| 5 g | Warenkorb auf Verfügbarkeit prüfen | CHF 3’390.00 |
Über diesen Artikel
Form:
powder
Assay:
≥90% (agarose gel electrophoresis)
Biological source:
bovine thyroid
Mol wt:
~670 kDa
Technischer Dienst
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Unterstützung erhaltenbiological source
bovine thyroid
Quality Level
assay
≥90% (agarose gel electrophoresis)
form
powder
mol wt
~670 kDa
composition
Iodine, ≥0.20%
nitrogen analysis
13.0-16.0% total
ash
≤4%
solubility
H2O: 20 mg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... TG(280706)
Application
Wird oft als Träger-Protein für die Produktion von Antikörpern eingesetzt. Sein Vorteil ist die große Zahl von Tyrosinresten, die für die Konjugation in Diazo-Reaktionen verwendet werden können.
Bovine thyroglobulin was shown to stimulate proliferation in rat thyroid follicular cells as well as in primary porcine thyroid epithelial cells. This effect was mediated through PI3K signaling.
Biochem/physiol Actions
Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.
Bovine thyroglobulin is a large, tetrameric glycoprotein produced in the thyroid gland as a precursor to thyroid hormones. Its large size and absence from plasma under normal conditions makes it very immunogenic and reduces the chance that antibodies to this carrier protein will cross-react with plasma proteins in immunoassays. Haptens may be conjugated to thyroglobulin via accessible secondary amines.
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Dieser Artikel | |||
|---|---|---|---|
| biological source bovine thyroid | biological source bovine thyroid | biological source Porcine thyroid | biological source bovine thyroid |
| assay ≥90% (agarose gel electrophoresis) | assay - | assay - | assay ≥90% (SDS-PAGE) |
| form powder | form powder | form powder | form lyophilized solid |
| mol wt ~670 kDa | mol wt ~670 kDa | mol wt ~670 kDa | mol wt - |
| Gene Information cow ... TG(280706) | Gene Information cow ... TG(280706) | Gene Information pig ... TG(100156471) | Gene Information - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
Product Information Sheet
Mahsa Hadidi et al.
Biotechnology progress, 32(6), 1531-1538 (2016-10-22)
Charged polysaccharides are used in the food industry, as cosmetics, and as vaccines. The viscosity, thermodynamics, and hydrodynamic properties of these charged polysaccharides are known to be strongly dependent on the solution ionic strength because of both inter- and intramolecular
Laura Gámez-Díaz et al.
Immunology and cell biology, 95(9), 789-802 (2017-06-28)
Biallelic mutations in the human lipopolysaccharide responsive beige-like anchor (LRBA) gene lead to a primary immunodeficiency known as LRBA deficiency, characterized by a broad range of clinical manifestations including autoimmunity, organomegaly, hypogammaglobulinemia and recurrent infections. Considering the phenotypic heterogeneity in
N Murat Karabacak et al.
Molecular & cellular proteomics : MCP, 8(4), 846-856 (2008-12-17)
Top-down and bottom-up mass spectrometry methods can generate gas phase fragments and use these to identify proteins. Top-down methods, in addition, can provide the mass of the protein itself and therefore additional structural information. Despite the conceptual advantage of top-down
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T1001-1G | 04061837336201 |
| T1001-500MG | 04061837336225 |
| T1001-5G | 04061837336232 |
| T1001-100MG | 04061837336195 |