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M0317
Microsomes from Liver, Pooled
from human
Synonym(e):
Liver Microsomes
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Über diesen Artikel
NACRES:
NA.47
UNSPSC Code:
12161501
Application
Microsomes from liver have been used to study the in vitro effect of Clinacanthus nutans leaves on the activity of cytochrome P450 3A4 and 2E1.
Biochem/physiol Actions
Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.
Source of drug metabolizing enzymes, including cytochrome P-450.
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| biological source human | biological source mouse (CD-1) | biological source mouse (CD-1) | biological source rat (Sprague-Dawley) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| packaging vial of ~10 mg | packaging vial of ~10 mg | packaging vial of 1.0 mL | packaging vial of ~20 mg |
| storage temp. −70°C | storage temp. −70°C | storage temp. −70°C | storage temp. −70°C |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
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Lagerklasse
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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