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F5900
Monoclonal Anti-Interleukin-2−Carboxyfluorescein antibody produced in mouse
clone 5334, purified immunoglobulin, buffered aqueous solution
Synonym(e):
Monoclonal Anti-Interleukin-2, Monoclonal Anti-IL-2
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Über diesen Artikel
NACRES:
NA.41
UNSPSC Code:
51111800
Conjugate:
carboxyfluorescein conjugate
Clone:
5334, monoclonal
Application:
FACS
Citations:
3
biological source
mouse
Quality Level
conjugate
carboxyfluorescein conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5334, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
flow cytometry: suitable
isotype
IgG1
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... IL2(3558)
General description
Interleukin-2 (IL-2) also refers as T Cell Growth Factor is a cytokine produced by certain subsets of T lymphocytes. It plays various functions like inducing interferon γ and B cell growth factor secretion as well as affecting the activation and proliferation of NK cells. It also has a vital role in modulating the expression of the IL-2 receptor and can facilitate B cell growth and differentiation. Monoclonal anti-Interleukin-2−Carboxyfluorescein antibody reacts specifically with human IL-2.
Immunogen
recombinant human IL-2
Application
Monoclonal anti-Interleukin-2−Carboxyfluorescein antibody can be used in flow cytometry assays for identifying intracytoplasmic cytokines and for enumerating cytokine producing cells present in a mixed population.
Biochem/physiol Actions
The conjugates will identify and quantitate cells containing intracellular forms of human IL-2 by flow cytometry.
Physical form
Solution in phosphate buffered saline containing 0.1% sodium azide.
Preparation Note
Purified antibody is conjugated to carboxyfluorescein.
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Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
Instructions
D A Morgan et al.
Science (New York, N.Y.), 193(4257), 1007-1008 (1976-09-10)
Selective growth of T lymphocytes occurred when unfractionated normal human bone marrow cells were cultured with conditioned medium obtained from phytohemagglutinin-stimulated normal human lymphocytes (Ly-CM). Cultures of up to 90 percent T cells have been maintained for more than 9
T A Waldmann et al.
The Journal of experimental medicine, 160(5), 1450-1466 (1984-11-01)
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2. Resting normal B cells and unselected B cell lines established from normal individuals were Tac antigen negative.
K A Smith et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(3), 864-868 (1985-02-01)
The cell surface density of high-affinity membrane receptors for the T-lymphocytotrophic hormone interleukin 2 (IL-2) determines the rate of T-cell-cycle progression. Since 10-fold greater numbers of IL-2 receptor molecules were found by using a radiolabeled monoclonal antibody reactive with IL-2
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F5900-100TST | 04061829671402 |