F5135

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

collagenase substrate, chromogenic

• Synonym(e): N-[3-(2-Furyl)-acryloyl]-L-leucyl-glycyl-L-prolyl-L-alanin
• Empirische Formel (Hill-System): C₂₃H₃₂N₄O₇
• CAS-Nummer: 78832-65-2
• Molekulargewicht: 476.52
• UNSPSC Code: 12352202
• PubChem Substance ID: 329799652
• NACRES: NA.32
• MDL number: MFCD00133552

Eigenschaften

• Produktname: N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala,
• Quality Segment: 200
• UniProt accession no.: Q02111
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](NC(=O)\C=C\c1ccco1)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(O)=O
• InChI: 1S/C23H32N4O7/c1-14(2)12-17(26-19(28)9-8-16-6-5-11-34-16)21(30)24-13-20(29)27-10-4-7-18(27)22(31)25-15(3)23(32)33/h5-6,8-9,11,14-15,17-18H,4,7,10,12-13H2,1-3H3,(H,24,30)(H,25,31)(H,26,28)(H,32,33)/b9-8+/t15-,17-,18-/m0/s1
• InChI key: ZLFQNOJSYZSINX-PVJKAEHXSA-N
• Gene Information: mouse ... Prkcq(18761)

Beschreibung

General description

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala or FALGPA is a synthetic substance which resemble the primary structure of collagen, and is hydrolyzed by all known collagenases.[1]

Substrate for collagenase.

Application

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala has been used for use in FALGPA assay performed using GBS (Group B Streptococci) USF704.[2]

Biochem/physiol Actions

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala or FALGPA is hydrolyzed by collagenases and the optimum pH for hydrolysis is 7.4.[1]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)