D4010

2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate

≥96% (HPLC), synthetic (organic), powder

• Synonym(e): 2′-deoxy-, 5′-triphosphate sodium salt, Guanosine, dGTP sodium salt hydrate
• Empirische Formel (Hill-System): C₁₀H₁₆N₅O₁₃P₃ · xNa⁺ · yH₂O
• CAS-Nummer: 18423-40-0
• Molekulargewicht: 507.18 (anhydrous free acid basis)
• MDL number: MFCD01311036
• UNSPSC Code: 41106305
• NACRES: NA.51
• PubChem Substance ID: 24893806
• Assay: ≥96% (HPLC)
• Biological source: synthetic (organic)
• Form: powder
• Storage temp.: −20°C

Eigenschaften

• Produktname: 2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate, ≥96% (HPLC)
• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥96% (HPLC)
• form: powder
• shipped in: dry ice
• storage temp.: −20°C

Beschreibung

Application

2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate has been used:

• as a component in a polymerase chain reaction (PCR) mixture for PCR product formation using AM-toxin primers[1]
• as an internal standard to improve the analytical performance of capillary electrophoresis (CE) analysis for the evaluation of the cleanup process[2]
• as a putative substrate in in vitro enzyme activity assay to incubate with nudix hydrolase 15 (NUDT15) protein for the evaluation of putative NUDT15 inhibitors[3]

Biochem/physiol Actions

Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity, and kinetics of various nucleoside-triphosphatases (NTPase) and ribonucleotide reductases.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type N95 (US)