Fortfahren mit
B8181
BID human
≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution
Anmelden zur Ansicht der Organisations- und Vertragspreise.
Größe auswählen
Ansicht ändern
| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 50 μg | Warenkorb auf Verfügbarkeit prüfen | CHF 758.00 |
Über diesen Artikel
Form:
buffered aqueous solution
Assay:
≥95% (SDS-PAGE)
Recombinant:
expressed in E. coli
Mol wt:
22 kDa by SDS-PAGE (reducing)
CHF 758.00
Warenkorb auf Verfügbarkeit prüfen
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhaltenBiochem/physiol Actions
Regulates outer mitochondrial membrane permeability, pro-apoptotic, causes release of cytochrome c from mitochondrial intermembrane space to cytosol.
Physical form
Solution, 0.2 μm filtered, in 25 mM HEPES, pH 7.5, and 0.1 M KCl.
Analysis Note
Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria.
Other Notes
Human BID (195 amino acid residues) is a member of the Bcl-2 family (accession number NM 001196).
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| recombinant expressed in E. coli | recombinant expressed in NSO cells | recombinant expressed in NSO cells | recombinant expressed in CHO cells |
| assay ≥95% (SDS-PAGE) | assay >95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay >95% (SDS-PAGE) |
| mol wt 22 kDa by SDS-PAGE (reducing) | mol wt 30 kDa by SDS-PAGE (reducing), 65 kDa by SDS-PAGE (reducing) (doublet) | mol wt 60-65 kDa by SDS-PAGE (reducing) | mol wt monomer ~180 kDa by SDS-PAGE (non-reducing), monomer ~80 kDa by SDS-PAGE (reducing) |
| form buffered aqueous solution | form lyophilized powder | form lyophilized powder | form liquid |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
flash_point_f
Not applicable
flash_point_c
Not applicable
wgk
nwg
Lagerklasse
12 - Non Combustible Liquids
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
X Luo et al.
Cell, 94(4), 481-490 (1998-09-04)
We report here the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as Fas and TNF. Peptide mass fingerprinting identified this protein
J Zha et al.
Science (New York, N.Y.), 290(5497), 1761-1765 (2000-12-02)
Many apoptotic molecules relocate subcellularly in cells undergoing apoptosis. The pro-apoptotic protein BID underwent posttranslational (rather than classic cotranslational) N-myristoylation when cleavage by caspase 8 caused exposure of a glycine residue. N-myristoylation enabled the targeting of a complex of p7
H Li et al.
Cell, 94(4), 491-501 (1998-09-04)
We report here that BID, a BH3 domain-containing proapoptotic Bcl2 family member, is a specific proximal substrate of Casp8 in the Fas apoptotic signaling pathway. While full-length BID is localized in cytosol, truncated BID (tBID) translocates to mitochondria and thus
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B8181-50UG | 04061838070302 |