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87787

6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-on -hydrochlorid

suitable for chemiluminescence, ≥98.0% (HPLC)

Synonym(e):

2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-on -hydrochlorid, Cypridina Luciferin Methoxy-analog, MCLA

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Über diesen Artikel

Empirische Formel (Hill-System):
C14H13N3O2 · HCl
CAS-Nummer:
Molekulargewicht:
291.73
UNSPSC Code:
12352200
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5838857


description

luminescence test: Emmax465 nm, 0.1 M Tris pH 8.5; after addition of H2O2 (Chemiluminescence: in 0.1 M Tris pH 8.5; after addition of H2O2)

assay

≥98.0% (HPLC)

form

powder

solubility

DMSO: soluble, H2O: soluble

suitability

suitable for chemiluminescence

SMILES string

Cl[H].COc1ccc(cc1)C2=CN3C(=O)C(C)=NC3=CN2

InChI

1S/C14H13N3O2.ClH/c1-9-14(18)17-8-12(15-7-13(17)16-9)10-3-5-11(19-2)6-4-10;/h3-8,15H,1-2H3;1H

InChI key

KGMPQNFFCUDXSO-UHFFFAOYSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Erzeugung von Chemilumineszenz durch die Reaktion mit Superoxid O2 oder Singulett-Sauerstoff. Wird in der Leukozyten-Forschung verwendet[1][2][3].


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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A Takahashi et al.
FEBS letters, 261(2), 369-372 (1990-02-26)
To investigate O2- generation in in situ lungs of rats treated with drugs to induce experimental acute respiratory distress syndrome, phorbol myristate acetate (PMA) or endotoxin were injected into rats, who had been continuously infused with 2(methyl-6-[p-methoxyphenyl]-3,7-dihydroimidazo[1,2-alpha]pyraz in-3-one (MCLA) and
Yasuhiro Kambayashi et al.
Journal of clinical biochemistry and nutrition, 41(1), 68-75 (2008-04-09)
We have proposed that diacylglycerol hydroperoxide-induced unregulated signal transduction causes oxidative stress-related diseases. In this study, we investigated which molecular species of diacylglycerol hydroperoxide activated human peripheral neutrophils. All diacylglycerol hydroperoxides, diacylglycerol hydroxides, and diacyglycerols tested in the present study
Taeko Mizutani et al.
Journal of oleo science, 65(12), 993-1001 (2016-11-11)
Sodium lauryl sulfate (SLS), a representative anionic surfactant, is well-known to induce rough skin following single or multiple topical applications. The mechanism by which SLS induces rough skin is thought to result from the disruption of skin moisture function consisting



Global Trade Item Number

SKUGTIN
87787-10MG-F04061833278383

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