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47568
5-Fluor-L-tryptophan
≥98.0% (HPLC)
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 25 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 119.00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C11H11FN2O2
CAS-Nummer:
Molekulargewicht:
222.22
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352202
MDL number:
Beilstein/REAXYS Number:
5052680
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Unterstützung erhaltenQuality Level
assay
≥98.0% (HPLC)
form
powder
optical purity
enantiomeric ratio: ≥99.5:0.5 (HPLC)
mp
270-280 °C
storage temp.
2-8°C
SMILES string
N[C@@H](Cc1c[nH]c2ccc(F)cc12)C(O)=O
InChI
1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1
InChI key
INPQIVHQSQUEAJ-VIFPVBQESA-N
Application
Biochem/physiol Actions
5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
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Dieser Artikel | |||
|---|---|---|---|
| form powder | form powder or crystals | form powder | form powder |
| assay ≥98.0% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (TLC) | assay ≥98.0% (HPLC) |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| mp 270-280 °C | mp - | mp - | mp - |
| optical purity enantiomeric ratio: ≥99.5:0.5 (HPLC) | optical purity - | optical purity - | optical purity - |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dereje Abate Negatu et al.
mBio, 10(2) (2019-03-28)
Indole propionic acid (IPA), produced by the gut microbiota, is active against Mycobacterium tuberculosisin vitro and in vivo However, its mechanism of action is unknown. IPA is the deamination product of tryptophan (Trp) and thus a close structural analog of
G S Rule et al.
Biochemistry, 26(2), 549-556 (1987-01-27)
In this study we demonstrate the potential of combining fluorine-19 nuclear magnetic resonance (NMR) spectroscopy with molecular genetics. We are using the membrane-bound enzyme D-lactate dehydrogenase of Escherichia coli as a model system to characterize interactions between proteins and lipids.
E W Miles et al.
Biochemistry, 25(15), 4240-4249 (1986-07-29)
We are exploring the active site and the mechanism of the pyridoxal phosphate dependent reactions of the bacterial tryptophan synthase alpha 2 beta 2 complex by use of substrate analogues and of reaction intermediate analogues. Fluorine-19 nuclear magnetic resonance studies
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 47568-25MG-F | 04061831579260 |