Direkt zum Inhalt
Merck
Alle Fotos(1)

Dokumente

A115

Supelco

Amitriptylin-Metabolit, (±)-E-10-hydroxyliert-

analytical standard

Synonym(e):

(±)-(E)-5-[3-(Dimethylamino)-propyliden]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):
C20H23NO
CAS-Nummer:
64520-05-4
Molekulargewicht:
293.40
MDL-Nummer:
MFCD00069200
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329770681
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

200

Form

solid

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Farbe

white

mp (Schmelzpunkt)

97-99 °C

Löslichkeit

0.1 M HCl: soluble
H2O: insoluble
methanol: soluble

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

CN(C)CC\C=C1/c2ccccc2CC(O)c3ccccc13

InChI

1S/C20H23NO/c1-21(2)13-7-12-17-16-9-4-3-8-15(16)14-20(22)19-11-6-5-10-18(17)19/h3-6,8-12,20,22H,7,13-14H2,1-2H3/b17-12+

InChIKey

GHWBJXOKAFHZAI-SFQUDFHCSA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Verwandte Kategorien

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Metabolit von Amitriptylin, tricyclisches Antidepressivum; Chromatographie-Standard.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
FN10182301
FN06022219
FN04232005
FN04301906
FN12191701

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Determination of tricyclic antidepressants in body fluids and organ material by HPLC.
Wedy, et al.
Fresenius Journal of Analytical Chemistry, 332, 266-266 (1988)
F Coudoré et al.
Cell biology and toxicology, 13(2), 131-137 (1997-02-01)
Biotransformation of amitriptyline (AMI) was studied at different intervals in freshly isolated hepatocytes from healthy or streptozocin-induced diabetic rats in order to investigate the influence of the diabetic state. Levels of free and conjugated AMI, demethylated and hydroxylated metabolites, were
X H Zhang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 28(2), 85-91 (1993-01-01)
The demethylation and hydroxylation of amitriptyline were calculated from the ratios between the area under concentration--time curve (AUC) of amitriptyline and its three metabolites in eight healthy Chinese volunteers after a single oral dose of 100 mg amitriptyline. Great interindividual
K Shimoda et al.
Journal of clinical psychopharmacology, 15(3), 175-181 (1995-06-01)
We measured the concentrations in plasma of amitriptyline and its metabolites, nortriptyline and geometric isomers of 10-hydroxynortriptyline and 10-hydroxyamitriptyline, in 73 Japanese psychiatric patients receiving amitriptyline hydrochloride (Tryptanol; Banyu Pharmaceutical Co. Ltd., Tokyo, Japan) by high-performance liquid chromatography. Although there
D R Jones et al.
Journal of chromatography, 278(2), 291-299 (1983-12-09)
A selective, sensitive method for the determination of amitriptyline and its metabolites is described. This method involves liquid-liquid extraction and capillary gas chromatography with nitrogen-sensitive detection. The detection limits of amitriptyline, nortriptyline, 10-hydroxy(E)amitriptyline, 10-hydroxy(E)nortriptyline, and 10-hydroxy(Z)nortriptyline were slightly less than
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.