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Merck

69745

Supelco

δ-Tocotrienol

analytical standard

Synonym(e):

(R)-δ-Tocotrienol, 8-Methyl-tocotrienol, [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol

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About This Item

Empirische Formel (Hill-System):
C27H40O2
CAS-Nummer:
Molekulargewicht:
396.61
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Biologische Quelle

Elaeis guineensis

Qualitätsniveau

Qualität

analytical standard

Assay

≥97.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Farbe

colorless to amber

Anwendung(en)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

Format

neat

Lagertemp.

−20°C

SMILES String

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC[C@]1(C)CCc2cc(O)cc(C)c2O1

InChI

1S/C27H40O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1

InChIKey

ODADKLYLWWCHNB-LDYBVBFYSA-N

Verwandte Kategorien

Allgemeine Beschreibung

δ-Tocotrienol can be found in coconut oil, palm oil, and cereal grains such as barley, oats, wheat and rye.
δ-Tocotrienol is known as one of the homologs of Vitamin E.

Anwendung

δ-Tocotrienol may be used as an analytical reference standard for the determination of δ-tocotrienol in:
  • Food samples of vegetable origin by high performance liquid chromatography-fluorescene detection (HPLC-FLD).
  • Chicken meat samples by LC-FLD.
  • Cereals by normal phase HPLC-FLD.
  • Rice bran samples by one-step equilibrium extraction method coupled to reversed-phase HPLC combined with dual wavelength ultraviolet-visible (UV-Vis) detector.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

A rapid procedure for analysing rice bran tocopherol, tocotrienol and gamma-oryzanol contents.
Chen MH and Bergman CJ
J. Food Compos. Anal., 18(2-3), 139-151 (2005)
Determination of carotene, tocopherols and tocotrienols in residue oil from palm pressed fiber using pressurized liquid extraction-normal phase liquid chromatography
Sanagi MM, et al.
Analytica Chimica Acta, 538(1-2), 71-76 (2005)
Merriline M Satyamitra et al.
Radiation research, 175(6), 736-745 (2011-03-26)
δ-Tocotrienol (DT3), a vitamin E isoform, is associated with strong antioxidant and immunomodulatory properties. We confirmed the potent antioxidant activity in membrane systems and showed that DT3 is an effective radiation protector and mitigator. DT3 (4 μM, P < 0.001)
Pamela J Hodul et al.
PloS one, 8(2), e52526-e52526 (2013-02-09)
Vitamin E δ-tocotrienol has been shown to have antitumor activity, but the precise molecular mechanism by which it inhibits the proliferation of cancer cells remains unclear. Here, we demonstrated that δ-tocotrienol exerted significant cell growth inhibition pancreatic ductal cancer (PDCA)
N Zaiden et al.
Journal of atherosclerosis and thrombosis, 17(10), 1019-1032 (2010-08-13)
Present study aimed to elucidate the suppression of serum lipids by gamma- and delta-tocotrienol (γδT3). The lipid-lowering effects of γδT3 were investigated using HepG2 liver cell line, hypercholesterolemic mice and borderline-high cholesterol patients. In-vitro results demonstrated two modes of action.

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