5.08017

nor-Binaltorphimine Dihydrochloride

≥98% (HPLC), solid, κ-opioid receptor antagonist, Calbiochem

• Synonym(e): nor-Binaltorphimine Dihydrochloride, Norbinaltorphimine, nor-BNI, κ Opioid Receptor Antagonist, nor-Binaltorphimine
• Empirische Formel (Hill-System): C₄₀H₄₃N₃O₆ · 2HCl
• CAS-Nummer: 105618-26-6
• Molekulargewicht: 734.71
• MDL-Nummer: MFCD00069374
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• product name: nor-Binaltorphimine Dihydrochloride,
• Assay: ≥98% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white to off-white
• Löslichkeit: water: 50 mM
• Lagertemp.: −20°C
• InChI: 1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2
• InChIKey: GYEXSFKLGQBRBJ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.

Biochem./physiol. Wirkung

Primary Target
kappa opioid receptor

Warnhinweis

Toxicity: Standard Handling (A)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sonstige Hinweise

Kishioka, S., et al. 2013. Neurosci. Letters.In press.

Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable