264151

Caspase-3 Substrate VII, Fluorogenic

Fluorogenic caspase-3 substrate.

• Synonym(e): Caspase-3 Substrate VII, Fluorogenic, Ac-DEVD-AFC
• Empirische Formel (Hill-System): C₃₀H₃₄F₃N₅O₁₃
• Molekulargewicht: 729.61
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: lyophilized solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated; protect from light
• Farbe: white
• Löslichkeit: DMSO: 5 mg/mL
• Fluoreszenz: λ_ex ~400 nm; λ_em ~505 nm
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10.

Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Fluorogenic caspase-3 substrate

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Standard Handling (A)

Sequenz

Ac-Asp-Glu-Val-Asp-AFC

Rekonstituierung

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sonstige Hinweise

Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable