07-419
Anti-SHP-1/SHPTP-1 Antibody
Upstate®, from rabbit
Synonym(e):
Anti-DRPLA
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 200 μg | Warenkorb auf Verfügbarkeit prüfen | CHF 438.00 |
Über diesen Artikel
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
13
CHF 438.00
Warenkorb auf Verfügbarkeit prüfen
Für Ihr Target ist ein rekombinanter, konservierungsmittelfreier Antikörper verfügbar. Probieren Sie ZRB2813
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Unterstützung erhaltenbiological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
General description
65kDa
Immunogen
Full-length glutathione transferase SHP-1 fusion protein, purified from bacteria
Application
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
This Anti-SHP-1/SHPTP-1 Antibody is validated for use in IP, WB for the detection of SHP-1/SHPTP-1.
Biochem/physiol Actions
SHP1
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide
Format: Purified
Protein A purified
Preparation Note
1 year at 2-8°C
Analysis Note
Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for mingels.
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for mingels.
routinely evaluated by immunoblot in RIPA lysates from human A431 carcinoma cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| clone polyclonal | clone NL213, monoclonal | clone polyclonal | clone HG213, monoclonal |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source rabbit | biological source rabbit | biological source rabbit | biological source rabbit |
| antibody form purified immunoglobulin | antibody form culture supernatant | antibody form purified immunoglobulin | antibody form unpurified |
| species reactivity human | species reactivity human, mouse | species reactivity mouse | species reactivity human |
| shipped in wet ice | shipped in dry ice | shipped in dry ice | shipped in wet ice |
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Lagerklasse
10 - Combustible liquids
wgk
WGK 1
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Erythropoietin induces sustained phosphorylation of STAT5 in primitive but not definitive erythrocytes generated from mouse embryonic stem cells.
Kazue Tsuji-Takayama, Takeshi Otani, Toshiya Inoue, Shuji Nakamura, Ryuichi Motoda et al.
Experimental Hematology null
Thierry Voisin et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 22(6), 1993-2002 (2008-01-17)
Orexins acting at the G protein-coupled receptor (GPCR) OX1R have recently been shown to promote dramatic apoptosis in cancer cells. We report here that orexin-induced apoptosis is driven by an immunoreceptor tyrosine-based inhibitory motif (ITIM) (IIY(358)NFL) present in the OX1R.
Santosh Kumar et al.
Journal of immunology (Baltimore, Md. : 1950), 194(2), 817-826 (2014-12-17)
Signaling by immunoreceptors is often initiated by phosphorylation of cytosolic tyrosines, which then recruit effector molecules. In the case of MHC class I-specific inhibitory receptors, phosphorylation of cytosolic tyrosine residues within ITIMs results in recruitment of a protein tyrosine phosphatase