T1126
Thyroglobulin aus Schweineschilddrüse
powder
Synonym(e):
TG human
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100 MG
€ 237,00
500 MG
€ 684,00
1 G
€ 1.190,00
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100 MG
€ 237,00
500 MG
€ 684,00
1 G
€ 1.190,00
About This Item
Empfohlene Produkte
Biologische Quelle
Porcine thyroid
Form
powder
Mol-Gew.
~670 kDa
Zusammensetzung
Iodine, ≥0.3%
Stickstoffbestimmung
14.0-17.5% total
Methode(n)
protein purification: suitable
Asche
≤4%
pI
4.58
UniProt-Hinterlegungsnummer
Lagertemp.
−20°C
Angaben zum Gen
pig ... TG(100156471)
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Biochem./physiol. Wirkung
Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin. [1]
Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Sonstige Hinweise
Electrophoretically heterogeneous.
Angaben zur Herstellung
When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Sanathana Konugolu Venkata Sekar et al.
Scientific reports, 8(1), 10015-10015 (2018-07-04)
Thyroid plays an important role in the endocrine system of the human body. Its characterization by diffuse optics can open new path ways in the non-invasive diagnosis of thyroid pathologies. Yet, the absorption spectra of tyrosine and thyroglobulin-key tissue constituents
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L D Kohn et al.
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Iodide transport by thyrocytes involves porters on the apical and basal surfaces of the cell facing the follicular lumen and bloodstream, respectively. Recent work identifies pendrin as an apical porter and shows that follicular thyroglobulin is a transcriptional regulator of
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