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N0258

N-Nitrosodiethylamin

ISOPAC®

Synonym(e):

Diethylnitrosamin

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Ihnen/SKUVerfügbarkeitPreis
1 g
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€ 94,00

Über diesen Artikel

Lineare Formel:
(C2H5)2NNO
CAS-Nummer:
Molekulargewicht:
102.14
UNSPSC Code:
12352116
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-226-1
Beilstein/REAXYS Number:
1744991
MDL number:
Form:
liquid

€ 94,00


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Quality Segment

form

liquid

bp

177 °C (lit.)

density

0.95 g/mL (lit.)

SMILES string

CCN(CC)N=O

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI key

WBNQDOYYEUMPFS-UHFFFAOYSA-N

Application

N-Nitrosodiethylamine (NDEA) has been used as a hepatocarcinogen/DNA damaging agent. It has been used as a calibration standard for gas–liquid chromatography.

Biochem/physiol Actions

N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

Packaging

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

Preparation Note

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

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Dieser Artikel
N07564426871466652
form

liquid

form

liquid

form

-

form

liquid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

bp

177 °C (lit.)

bp

177 °C (lit.)

bp

177 °C (lit.)

bp

-

density

0.95 g/mL (lit.)

density

0.95 g/mL (lit.)

density

0.95 g/mL (lit.)

density

-


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Questions

1–7 of 7 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is Product N0258, N-nitrosoethylamine, a solid or a liquid? Why is the package size expressed in grams?

    1 answer
    1. This product is neat liquid. The package size is in grams but can be converted to volume by using the density of 0.95 g/mL.

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  4. How can I store solutions of Product N0258, N-Nitrosodiethylamine?

    1 answer
    1. The product should be stable in neutral solution, but it is unstable with strong acid and heat. N-nitroso amine compounds are relatively stable when dissolved in aqueous solutions at physiological pH. But they are generally light sensitive, so stock solutions should be kept cool and protected from light.

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  5. What is the solubility of Product N0258, N-Nitrosodiethylamine?

    1 answer
    1. According to the chemicals encyclopedia published by the Royal Society of Chemistry, 12th edition, this compound is soluble in water, ether and alcohol.

      Helpful?

  6. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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