N0756

N-Nitrosodiethylamin

liquid, nitrosamine

• Synonym(e): Diethylnitrosamin
• Lineare Formel: (C₂H₅)₂NNO
• CAS-Nummer: 55-18-5
• Molekulargewicht: 102.14
• Beilstein: 1744991
• EG-Nummer: 200-226-1
• MDL-Nummer: MFCD00013890
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24897440
• NACRES: NA.77

Eigenschaften

• Produktbezeichnung: N-Nitrosodiethylamin, liquid
• Form: liquid
• Farbe: yellow
• bp: 177 °C (lit.)
• Dichte: 0.95 g/mL (lit.)
• SMILES String: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• InChIKey: WBNQDOYYEUMPFS-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

N-Nitrosodiethylamine belongs to the nitrosamines category of nitrogenous disinfection byproduct. It is also generated in chlorine based water treatment plants.

Anwendung

N-Nitrosodiethylamine has been used to induce hepatocarcinogenesis in rat and mice.

Biochem./physiol. Wirkung

N-Nitrosodiethylamine (NDMA) is carcinogenic in all animal species tested. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. NDMA is acted upon by the cytochrome P450 system resulting in the formation of carcinogenic methyldiazonium ion. However microbes like Pseudomonas metabolize NDMA into N-nitromethylamine (NTMA) and formaldehyde.

Verpackung

Bulk Package

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H350,H412
• P-Sätze: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter