E7159

Exo2

≥98% (HPLC)

• Synonym(e): 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
• Empirische Formel (Hill-System): C₁₈H₁₈N₄O₂S
• CAS-Nummer: 304684-77-3
• Molekulargewicht: 354.43
• NACRES: NA.77
• PubChem Substance ID: 329799006
• UNSPSC Code: 12352200
• MDL number: MFCD00380179
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: DMSO: >20 mg/mL
• storage temp.: 2-8°C
• SMILES string: COc1cc(ccc1O)\C=N\Nc2ncnc3sc4CCCCc4c23
• InChI: 1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+
• InChI key: VFNUTEMVQGLDAG-ZVBGSRNCSA-N

Beschreibung

Biochem/physiol Actions

Exo2 acts as a chemical probe of intracellular transport.

Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective.

Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN).[1] It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi.[2]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable