This product is intended for research use only and is not to be used for unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses, or any type of consumption or application to humans or animals. This product is soluble in DMSO and insoluble in water. Stability once in solution has not been tested in-house. Other sources do not recommend storing the aqueous solution for more than one day.
A9719
Arachidonyl-2′-chloroethylamide hydrate
≥97% (HPLC), oil
Synonym(e):
ACEA
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Über diesen Artikel
Empirische Formel (Hill-System):
C22H36ClNO · xH2O
CAS-Nummer:
Molekulargewicht:
365.98 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
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Unterstützung erhaltenQuality Level
assay
≥97% (HPLC)
form
oil
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
storage condition
desiccated
color
brown-red
solubility
DMSO: soluble, H2O: insoluble
storage temp.
−20°C
SMILES string
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCCl
InChI
1S/C22H36ClNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
InChI key
SCJNCDSAIRBRIA-DOFZRALJSA-N
Gene Information
mouse ... Cnr1(12801), Cnr2(12802)
rat ... Cnr1(25248)
Verwandte Kategorien
1 of 4
Dieser Artikel | |||
|---|---|---|---|
| assay ≥97% (HPLC) | assay ≥98% (HPLC) | assay >98% (HPLC) | assay ≥98% (TLC) |
| form oil | form solid | form solid | form powder |
| drug control regulated under CDSA - not available from Sigma-Aldrich Canada | drug control - | drug control - | drug control - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 300 |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition desiccated | storage condition - | storage condition - | storage condition - |
Biochem/physiol Actions
Potent and selective neuronal CB1 cannabinoid receptor agonist.
Features and Benefits
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
Photosensitive; store under argon or nitrogen.
Lagerklasse
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Yahya I Asiri et al.
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Development of new analgesics is limited by shortcomings of existing preclinical screening assays such as wide variations in response, suitability for a narrow range of analgesics, and propensity to induce tissue damage. Our aim was to determine the feasibility of
Akiko Tsuchida et al.
Scientific reports, 8(1), 7017-7017 (2018-05-08)
GalNAc-disialyl Lc4 (GalNAc-DSLc4) was reported as a novel antigen that associated with malignant features of renal cell cancers (RCCs). To clarify roles of GalNAc-DSLc4 in malignant properties of RCCs, we identified B4GalNAc-T2 as a responsible gene for the synthesis of
Chris L Baker et al.
British journal of pharmacology, 142(8), 1361-1367 (2004-07-28)
The vasoactive effects of the synthetic cannabinoid (CB) arachidonyl-2-chloroethylamide (ACEA) was tested in the knee joints of urethane-anaesthetised rats. Experiments were also performed to determine whether these vasomotor responses could be blocked by the selective CB(1) receptor antagonists AM251 (N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide)
C J Hillard et al.
The Journal of pharmacology and experimental therapeutics, 289(3), 1427-1433 (1999-05-21)
Two subtypes of the cannabinoid receptor (CB1 and CB2) are expressed in mammalian tissues. Although selective antagonists are available for each of the subtypes, most of the available cannabinoid agonists bind to both CB1 and CB2 with similar affinities. We
Kristina B V Døssing et al.
Genes, 9(7) (2018-07-06)
Somatostatin (SST) analogues are used to control the proliferation and symptoms of neuroendocrine tumors (NETs). MicroRNAs (miRNA) are small non-coding RNAs that modulate posttranscriptional gene expression. We wanted to characterize the miRNAs operating under the control of SST to elucidate
Verwandter Inhalt
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Can the medicine be dissolved in deionized water or DMSO? How many months can the solution be stored after dissolution? What should be the storage conditions in degrees Celsius?
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