α-Cyano-4-hydroxycinnamic acid (α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA) is soluble in methanol (up to 50 mg/ml). It is also soluble at 10 mg/ml using 50% acetonitrile in 0.05% TFA for MALDI-MS. The acetonitrile concentration can be adjusted for individual preferences.For biological applications, it has been solubilized at 100 mM in DMSO or 50 mM in ethanol.
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α-Cyano-4-hydroxyzimtsäure
≥98% (TLC), powder, monocarboxylic acid transport inhibitor
Synonym(e):
α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA
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10 G
€ 54,00
25 G
€ 120,00
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10 G
€ 54,00
25 G
€ 120,00
About This Item
Lineare Formel:
HOC6H4CH=C(CN)CO2H
CAS-Nummer:
Molekulargewicht:
189.17
Beilstein:
3271427
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352106
PubChem Substanz-ID:
NACRES:
NA.77
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Produktbezeichnung
α-Cyano-4-hydroxyzimtsäure, ≥98% (TLC), powder
Qualitätsniveau
Assay
≥98% (TLC)
Form
powder
Farbe
yellow
mp (Schmelzpunkt)
245-250 °C (lit.)
Löslichkeit
H2O: slightly soluble
methanol: water: soluble
polar organic solvents: soluble
Lagertemp.
2-8°C
SMILES String
OC(=O)\C(=C\c1ccc(O)cc1)C#N
InChI
1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
InChIKey
AFVLVVWMAFSXCK-VMPITWQZSA-N
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Anwendung
α-Cyano-4-hydroxycinnamic acid is a useful hydrophobic matrix solution for matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry.[3] Antibiotics, peptide nucleic acids (a new class of DNA mimics), and proteins with masses as high as 66,000 Da have been successfully analyzed by using this as a matrix solution.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Skin Sens. 1B
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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Verwandter Inhalt
ZipTip® micro-SPE pipette tips are used as a single-step desalting, concentration, and purification tool for complex samples before mass spec analyses.
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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