5.05772

Pirenzepine Dihydrochloride

• Synonym(e): Pirenzepine Dihydrochloride, Muscarinic Acetylcholine Receptor (mAChR) M1 Antagonist, Pirenzepine dihydrochloride
• Empirische Formel (Hill-System): C₁₉H₂₁N₅O₂ · 2HCl
• CAS-Nummer: 28797-61-7
• Molekulargewicht: 424.32
• MDL number: MFCD00242717
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥99% (HPLC)
• Form: solid
• Storage condition: OK to freeze, protect from light

Eigenschaften

• assay: ≥99% (HPLC)
• Quality Segment: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: white
• solubility: water: 100 mM
• storage temp.: 2-8°C
• SMILES string: N4(CCN(CC4)C)CC(=O)[n]1c2ncccc2[nH][c](c3c1cccc3)=O
• InChI: 1S/C19H21N5O2/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24/h2-8H,9-13H2,1H3,(H,21,26)
• InChI key: RMHMFHUVIITRHF-UHFFFAOYSA-N

Beschreibung

General description

An antagonist selective for mAChR subtype M1. Used for studying the functional roles of M1 receptors in both central and peripheral nervous systems.

Biochem/physiol Actions

Primary Target
M1

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Shirey, K., et al., 2009. J. Neurosci.29, 14271.
Pelat, M., et al., 1999. Eur.J. Pharmacol.379, 117.
Burford NT, et al. 1996. Biochem. J.315, 883.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable