16-662
Magna ChIP® magnetische Protein G-Beads
Recombinant Protein G covalently bound to magnetic beads for use in chromatin immunoprecipitations (ChIP assays). These protein G beads provide users a more rapid, reproducible & efficient reagent for collecting immunocomplexes vs. agarose beads.
Synonym(e):
ChIP magnetic beads, ChIP magnetic G beads, Magnetic Chromatin Immunoprecipitation
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
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Über diesen Artikel
Quality Level
packaging
pkg of 1 mL
manufacturer/tradename
Magna ChIP®
particle size
~3 μm
shipped in
wet ice
storage temp.
2-8°C
General description
Application
Epigenetik und Zellkernfunktion
Physical form
Preparation Note
Analysis Note
Legal Information
Disclaimer
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Dieser Artikel | |||
|---|---|---|---|
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in dry ice |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| packaging pkg of 1 mL | packaging pkg of 1 mL | packaging pkg of 1 mL | packaging - |
| particle size ~3 μm | particle size ~3 μm | particle size ~3 μm | particle size - |
| manufacturer/tradename Magna ChIP® | manufacturer/tradename Magna ChIP® | manufacturer/tradename Magna ChIP® | manufacturer/tradename Magna ChIP® |
Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysenzertifikate (COA)
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Verwandter Inhalt
Chromatin-immunoprecipitation (ChIP) followed by next generation sequencing (ChIP-seq) of the immunoprecipitated DNA is a powerful tool for the investigation of protein:DNA interactions. To perform ChIP-seq, chromatin is isolated from cells or tissues (with or without chemical crosslinking) and fragmented. Antibodies recognizing chromatinassociated proteins of interest are used to enrich the sample for specific chromatin fragments. The DNA is recovered, sequenced on various NGS platforms, and aligned to a reference genome to determine specific protein binding loci. ChIP-seq studies have increased our knowledge of transcription factor biology, DNA methylation and histone modifications.
"Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. These changes can be cell- or tissue-specific, and can be passed on to multiple generations. Epigenetic regulation enriches DNAbased information, allowing a cell to vary its response across diverse biological and environmental contexts. Although epigenetic mechanisms are primarily centered in the nucleus, these mechanisms can be induced by environmental signals such as hormones, nutrients, stress, and cellular damage, pointing to the involvement of cytoplasmic and extracellular factors in epigenetic regulation."
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 16-662 | 04053252377167 |
| 16-662X | 04053252377174 |