1229409

Drospirenon

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 6β,7β:15β,16β -Dimethylen-3-oxo-17α-pregn-4-en-21,17-carbolacton, Dihydrospirorenon
• Empirische Formel (Hill-System): C₂₄H₃₀O₃
• CAS-Nummer: 67392-87-4
• Molekulargewicht: 366.49
• NACRES: NA.24
• PubChem Substance ID: 329749691
• UNSPSC Code: 41116107
• MDL number: MFCD00867350

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: drospirenone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: C[C@]12CCC(=O)C=C1[C@@H]3C[C@@H]3[C@@H]4[C@@H]2CC[C@@]5(C)[C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7
• InChI: 1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
• InChI key: METQSPRSQINEEU-HXCATZOESA-N
• Gene Information: human ... NR3C2(4306), PGR(5241)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Drospirenone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Drospirenone and Ethinyl Estradiol Tablets

Biochem/physiol Actions

Drospirenon ist ein Progestin der vierten Generation mit antimineralcorticoider und antiandrogener Aktivität, sowie starker Progestagenaktivität. Zwei aktuelle Studien zeigen, dass Drospirenon das Risiko von venösen Thromboembolien, im Vergleich zu Levonorgestrel, verdoppeln soll, obwohl andere Studien wenig zusätzliches Risiko fanden.

Gestagen der vierten Generation, Kontrazeptivum

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H360
• pcodes: P201 - P280 - P308 + P313
• Hazard Classifications: Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable