V4390

VUF 8430 dihydrobromide

≥97% (NMR)

• Synonym(e): 2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester, S-(2-guanidylethyl)-isothiourea
• Empirische Formel (Hill-System): C₄H₁₁N₅S· 2HBr
• CAS-Nummer: 100130-32-3
• Molekulargewicht: 323.05
• NACRES: NA.77
• PubChem Substance ID: 329829051
• UNSPSC Code: 12352200
• MDL number: MFCD01694605
• Assay: ≥97% (NMR)
• Form: solid
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥97% (NMR)
• form: solid
• storage condition: desiccated
• solubility: deionized water: 24 mg/mL
• storage temp.: room temp
• SMILES string: Br.Br.NC(=N)NCCSC(N)=N
• InChI: 1S/C4H11N5S.2BrH/c5-3(6)9-1-2-10-4(7)8;;/h1-2H2,(H3,7,8)(H4,5,6,9);2*1H
• InChI key: GPWJSTKHQMIXCA-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

VUF 8430 dihydrobromide is a potent histamine H4 receptor agonist, with a 33-fold selectivity over the histamine H3 receptor and negligible affinity for the other histamine receptor.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable