R8900

Ro 8-4304

solid

• Empirische Formel (Hill-System): C₂₁H₂₃FN₂O₃ · HCl
• Molekulargewicht: 406.88
• NACRES: NA.77
• PubChem Substance ID: 24277971
• UNSPSC Code: 12352200
• MDL number: MFCD03101333
• Form: solid

Eigenschaften

• form: solid
• Quality Segment: 100
• solubility: H₂O: ≤0.5 mg/mL
• originator: Roche
• storage temp.: 2-8°C
• SMILES string: Cl.NC(=O)c1ccc(OCCC(O)N2CCC(=CC2)c3ccc(F)cc3)cc1
• InChI: 1S/C21H23FN2O3.ClH/c22-18-5-1-15(2-6-18)16-9-12-24(13-10-16)20(25)11-14-27-19-7-3-17(4-8-19)21(23)26;/h1-9,20,25H,10-14H2,(H2,23,26);1H
• InChI key: NYFXHCMXYODFLP-UHFFFAOYSA-N
• Gene Information: human ... GRIN2B(2904)

Beschreibung

Biochem/physiol Actions

NR2B-selective, noncompetitive NMDA glutamate receptor antagonist

Features and Benefits

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves