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N8161
NS309
≥98% (HPLC), Ca2+-activated IK/SK potassium channel activator, solid
Synonym(e):
3-Oxime-6,7-dichloro-1H-indole-2,3-dione
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 5 mg | Warenkorb auf Verfügbarkeit prüfen | € 203,00 € 172,55 | |
| 25 mg | Warenkorb auf Verfügbarkeit prüfen | € 580,00 € 493,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C8H4Cl2N2O2
CAS-Nummer:
Molekulargewicht:
231.04
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
€ 172,55
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Unterstützung erhaltenProduktname
NS309, ≥98% (HPLC), solid
Quality Level
assay
≥98% (HPLC)
form
solid
color
yellow
solubility
DMSO: 22 mg/mL
storage temp.
2-8°C
SMILES string
O\N=C1\C(=O)Nc2c(Cl)c(Cl)ccc12
InChI
1S/C8H4Cl2N2O2/c9-4-2-1-3-6(5(4)10)11-8(13)7(3)12-14/h1-2,14H,(H,11,12,13)
InChI key
CVOUSAVHMDXCKG-UHFFFAOYSA-N
Biochem/physiol Actions
NS309 is a Ca2+-activated IK/SK potassium channel activator.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
air sensitive
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Dieser Artikel | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay >98% (HPLC) | assay ≥98% (HPLC) |
| form solid | form powder | form - | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility DMSO: 22 mg/mL | solubility DMSO: ≥20 mg/mL | solubility DMSO: soluble 20 mg/mL, H2O: insoluble | solubility DMSO: >20 mg/mL |
| color yellow | color orange | color orange | color white to off-white |
Lagerklasse
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Kanwal Sakhi et al.
The Journal of physiology, 592(4), 587-603 (2013-11-20)
Intrinsic daily or circadian rhythms arise through the outputs of the master circadian clock in the brain's suprachiasmatic nuclei (SCN) as well as circadian oscillators in other brain sites and peripheral tissues. SCN neurones contain an intracellular molecular clock that
Cara C Rada et al.
American journal of physiology. Endocrinology and metabolism, 307(10), E935-E943 (2014-09-25)
Proper placental perfusion is essential for fetal exchange of oxygen, nutrients, and waste with the maternal circulation. Impairment of uteroplacental vascular function can lead to pregnancy complications, including preeclampsia and intrauterine growth restriction (IUGR). Potassium channels have been recognized as
Fan-Fan Li et al.
Placenta, 58, 9-16 (2017-10-01)
Excessive constriction of placental chorionic plate arteries (CPAs) may be associated with preeclampsia (PE). Nitric oxide (NO) as well as intermediate and small Ca The location of IK IK This study provides evidence that dysregulated IK
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N8161-25MG | 04061832575117 |
| N8161-5MG | 04061834118442 |