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Sigma-Aldrich

Kynuramine dihydrobromide

monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline

Synonym(e):

3-(2-Aminophenyl)-3-oxopropanamine

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About This Item

Empirische Formel (Hill-System):
C9H12N2O · 2HBr
CAS-Nummer:
304-47-2
Molekulargewicht:
326.03
MDL-Nummer:
MFCD00050683
UNSPSC-Code:
12352204
PubChem Substanz-ID:
24896227
NACRES:
NA.32

product name

Kynuramine dihydrobromide, crystalline

Assay

≥97% (TLC)

Form

crystalline

Löslichkeit

water: 50 mg/mL, clear to slightly hazy

Lagertemp.

−20°C

SMILES String

Br.NCCC(=O)c1ccccc1N

InChI

1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H

InChIKey

YUPVVZSYBUIDQR-UHFFFAOYSA-N

Anwendung

Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase.

Biochem./physiol. Wirkung

Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm.

Substrate

Substrate for monoamine oxidase

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr
Berntssen MHG, et al.
Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)
Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system
Li G, et al.
Metabolic Brain Disease, 30(6), 1505-1514 (2015)
Izaviany da Silva Schmitz et al.
Molecular biology reports, 46(2), 2285-2292 (2019-02-14)
Oxidative stress occurs due to an imbalance between antioxidant defenses and pro-oxidant agents in brain. This condition has been associated to the pathogenesis of several brain diseases; therefore, increasing the use of compounds that exert antioxidant activity. Thus, the objective
Paolo Guglielmi et al.
Molecules (Basel, Switzerland), 24(3) (2019-02-01)
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B. The most important chiral compounds were separated into their single enantiomers and tested. The impact of
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