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Merck

G2505

Sigma-Aldrich

N-Glutaryl-L-Phenylalanin p-Nitroanilid

protease substrate

Synonym(e):

Glutaryl-L-phenylalanine 4-nitroanilide

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About This Item

Empirische Formel (Hill-System):
C20H21N3O6
CAS-Nummer:
Molekulargewicht:
399.40
Beilstein:
2919832
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
PubChem Substanz-ID:
NACRES:
NA.83

Assay

≥98% (HPLC)

Form

powder

Löslichkeit

methanol with 1 M NH4OH: 50 mg/mL, clear to slightly hazy

Lagertemp.

−20°C

SMILES String

OC(=O)CCCC(=O)N[C@@H](Cc1ccccc1)C(=O)Nc2ccc(cc2)[N+]([O-])=O

InChI

1S/C20H21N3O6/c24-18(7-4-8-19(25)26)22-17(13-14-5-2-1-3-6-14)20(27)21-15-9-11-16(12-10-15)23(28)29/h1-3,5-6,9-12,17H,4,7-8,13H2,(H,21,27)(H,22,24)(H,25,26)/t17-/m0/s1

InChIKey

LFZGBNATHRHOKZ-KRWDZBQOSA-N

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Anwendung

N-Glutaryl-L-phenylalanine p-nitroanilide has been used as a substrate to determine chymotrypsin activity.

Biochem./physiol. Wirkung

N-Glutaryl-L-phenylalanine p-nitroanilide is useful in testing α-chymotrypsin activity.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Kunden haben sich ebenfalls angesehen

Elsa Abuin et al.
Journal of colloid and interface science, 283(2), 539-543 (2005-02-22)
The rate of hydrolysis of N-glutaryl-L-phenylalanine p-nitroanilide (GPNA) catalyzed by alpha-chymotrypsin (alpha-CT) has been measured in aqueous solutions of dodecyltrimethylammonium bromide (DTAB) at concentrations below and above the critical micelle concentration, as well as in the absence of surfactant. Under
Elsa Abuin et al.
Journal of colloid and interface science, 308(2), 573-576 (2007-01-26)
The rate of N-glutaryl-L-phenylalanine p-nitroanilide hydrolysis catalyzed by alpha-chymotripsin has been measured in aqueous solutions of cetyltrimethylammonium bromide, tetradecyltrimethylammonium bromide, and dodecyltrimethylammonium bromide at concentrations below and above their critical micellar concentrations (CMC). For the three surfactants considered superactivity was
Takeshi Honda et al.
Chemical communications (Cambridge, England), (40)(40), 5062-5064 (2005-10-13)
A novel and facile method for the preparation of an enzyme-immobilized microreactor has been developed in which enzymes are immobilized as an enzyme-polymer membrane formed on the inner wall of the microchannel by a cross-linking polymerization method; the resulting microreactor
Anca Dragulescu-Andrasi et al.
Chemical communications (Cambridge, England), (2)(2), 244-246 (2005-02-23)
Guanidine-based peptide nucleic acid (GPNA) with a d-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.
Occurrence and identity of proteolytic bacteria in adult periodontitis.
D Grenier et al.
Journal of periodontal research, 29(5), 365-370 (1994-09-01)

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