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A6553

DL-2-Amino-5-phosphonovaleric acid lithium salt

~95%

Synonym(e):

DL-2-Amino-5-phosphonopentanoic acid, AP-5

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Über diesen Artikel

Lineare Formel:
C5H11NO5PLi
CAS-Nummer:
125229-62-1
Molekulargewicht:
203.06
NACRES:
NA.26
PubChem Substance ID:
24891104
UNSPSC Code:
12352106
MDL number:
MFCD00078901

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InChI

1S/C5H12NO5P.Li.H/c6-4(5(7)8)2-1-3-12(9,10)11;;/h4H,1-3,6H2,(H,7,8)(H2,9,10,11);;

SMILES string

[Li].NC(CCCP(O)(O)=O)C(O)=O

InChI key

QIVHTKSFMZBERS-UHFFFAOYSA-N

assay

~95%

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

Quality Level

100

Gene Information

rat ... Grik1(29559), Grin2a(24409), Grin2b(24410)

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Dieser Artikel
A8054A3785A7502
DL-2-Amino-5-phosphonovaleric acid lithium salt ~95%

Sigma-Aldrich

A6553

DL-2-Amino-5-phosphonovaleric acid lithium salt

D(−)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist

Sigma-Aldrich

A8054

D(−)-2-Amino-5-phosphonopentanoic acid

5-Aminolevulinic acid hydrochloride ≥98%

Sigma-Aldrich

A3785

5-Aminolevulinic acid hydrochloride

DL-Alanine ≥99% (HPLC)

Sigma-Aldrich

A7502

DL-Alanine

form

powder

form

powder

form

powder

form

powder

assay

~95%

assay

≥98% (TLC)

assay

≥98%

assay

≥99% (HPLC)

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

color

white to off-white

color

white

color

-

color

white to off-white

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

200

Gene Information

rat ... Grik1(29559), Grin2a(24409), Grin2b(24410)

Gene Information

mouse ... Grin2a(14811)
rat ... Grik1(29559), Grin2a(24409), Grin2b(24410), Grin2c(24411), Grin2d(24412)

Gene Information

-

Gene Information

-

Biochem/physiol Actions

Anticonvulsant; potent and selective antagonist for NMDA receptors.
DL-2-Amino-5-phosphonovaleric acid is a selective N-methyl-d-aspartate (NMDA) receptor antagonist used frequently in studies of neurological processes

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000227048
0000227048
0000142631
0000136619
0000074443

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Die Dokumentenbibliothek aufrufen

Guan Cao et al.
Journal of neurophysiology, 107(3), 902-912 (2011-11-25)
Long-term potentiation (LTP) is a form of synaptic plasticity thought to underlie memory; thus knowing its developmental profile is fundamental to understanding function. Like memory, LTP has multiple phases with distinct timing and mechanisms. The late phase of LTP (L-LTP)
Jessica M André et al.
Neuropharmacology, 60(4), 617-625 (2010-12-21)
NMDA glutamate receptors (NMDARs) and nicotinic acetylcholine receptors (nAChRs) are both involved in learning and synaptic plasticity. Increasing evidence suggests processes mediated by these receptors may interact to modulate learning; however, little is known about the neural substrates involved in
A Osorio-Espinoza et al.
Neuroscience, 176, 20-31 (2011-01-05)
The globus pallidus, a neuronal nucleus involved in the control of motor behavior, expresses high levels of histamine H(3) receptors (H(3)Rs) most likely located on the synaptic afferents to the nucleus. In this work we studied the effect of the
Thomas K Fung et al.
Synapse (New York, N.Y.), 65(7), 677-686 (2010-12-31)
Synaptic plasticity may depend not only on the afferent fibers but also on the recipient structure. The medial perforant path (MPP) from the entorhinalcortex projects to both the dentate gyrus (DG) and CA3, resulting in excitatory postsynaptic potentials (EPSPs) in
Brandon S Martin et al.
Journal of neurophysiology, 112(4), 890-902 (2014-05-23)
Fragile X syndrome (FXS) is the leading cause of inherited intellectual disability. Comorbidities of FXS such as autism are increasingly linked to imbalances in excitation and inhibition (E/I) as well as dysfunction in GABAergic transmission in a number of brain
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