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52194

Tetramethylrhodaminisothiocyanat–Dextran

average mol wt 500,000

Synonym(e):

TRITC-Dextran 500, TRITC-Dextran

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UNSPSC Code:
12352116
NACRES:
NA.32
MDL number:
MFCD00132418

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Unterstützung erhalten

biological source

synthetic

Quality Level

100

form

powder or crystals

mol wt

average mol wt 500,000

extent of labeling

0.001-0.008 mol/mol TRITC glucose

fluorescence

λex 550 nm; λem 575 nm±5 nm in 0.1 M Tris pH 8.0

application(s)

cell analysis

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Dieser Artikel
42874T1287T1162
Sigma-Aldrich

Sigma-Aldrich

52194

Tetramethylrhodamine isothiocyanate–Dextran

Sigma-Aldrich

Sigma-Aldrich

42874

Tetramethylrhodamine isothiocyanate–Dextran

Tetramethylrhodamine isothiocyanate–Dextran average mol wt 155,000

Sigma-Aldrich

T1287

Tetramethylrhodamine isothiocyanate–Dextran

Tetramethylrhodamine isothiocyanate–Dextran average mol wt 65,000-85,000

Sigma-Aldrich

T1162

Tetramethylrhodamine isothiocyanate–Dextran

biological source

synthetic

biological source

synthetic

biological source

synthetic (organic)

biological source

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

powder or crystals

form

powder

form

powder

form

powder

mol wt

average mol wt 500,000

mol wt

average mol wt 40,000

mol wt

average mol wt 155,000

mol wt

average mol wt 65,000-85,000

extent of labeling

0.001-0.008 mol/mol TRITC glucose

extent of labeling

0.001-0.008 mol/mol TRITC glucose

extent of labeling

~1 TRITC per 100 glucose residues

extent of labeling

~1 TRITC per 100 glucose residues

fluorescence

λex 550 nm; λem 575 nm±5 nm in 0.1 M Tris pH 8.0

fluorescence

λex 550 nm; λem 577 nm±5 nm in 0.1 M Tris pH 8.0

fluorescence

-

fluorescence

-

General description

Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 500, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. [1]The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.[2]

Application

Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 500) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCP4733
BCCM8923
BCCK6389
BCCK0028
BCCH0185

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Thea van der Wijk et al.
The Journal of biological chemistry, 278(41), 40020-40025 (2003-07-23)
Osmotic swelling of Intestine 407 cells leads to an immediate increase in cell surface membrane area as determined using the fluorescent membrane dye FM 1-43. In addition, as measured by tetramethylrhodamine isothiocyanate (TRITC)-dextran uptake, a robust (>100-fold) increase in the
Margaret Clarke et al.
Journal of cell science, 115(Pt 14), 2893-2905 (2002-06-26)
The vacuolar H(+)-ATPase (V-ATPase) is a multi-subunit enzyme that plays important roles in eukaryotic cells. In Dictyostelium, it is found primarily in membranes of the contractile vacuole complex, where it energizes fluid accumulation by this osmoregulatory organelle and also in
Ngo Bich Nga Nathalie Tran et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 116, 12-16 (2016-10-25)
Hair follicle research is currently focused on the development of drug-loaded nanocarriers for the targeting of follicular structures in the treatment of skin and hair follicle-related disorders. In the present study, a dual-label nanocarrier system was implemented in which FITC-labeled
Alexa Patzelt et al.
Journal of controlled release : official journal of the Controlled Release Society, 246, 174-182 (2016-09-20)
More and more investigations confirm that nanoparticles are incapable of overcoming the intact skin barrier in vivo. Do nanoparticles still have a future in dermal drug delivery? Unlike many other topically applied substances, nanoparticles have not been reported to utilize
Celine Mateo et al.
Neuron, 96(4), 936-948 (2017-11-07)
Resting-state signals in blood-oxygenation-level-dependent (BOLD) imaging are used to parcellate brain regions and define "functional connections" between regions. Yet a physiological link between fluctuations in blood oxygenation with those in neuronal signaling pathways is missing. We present evidence from studies
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