Direkt zum Inhalt
Merck
Alle Fotos(1)

Dokumente

27029

Sigma-Aldrich

Natriumcholat Hydrat

≥97.0% (dried material, NT)

Synonym(e):

3α,7α,12α-Trihydroxy-5β-cholan-24-säure Natriumsalz, Cholsäure Natriumsalz

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):
C24H39NaO5 · xH2O
CAS-Nummer:
206986-87-0
Molekulargewicht:
430.55 (anhydrous basis)
Beilstein:
3582354
EG-Nummer:
206-643-5
MDL-Nummer:
MFCD00150749
UNSPSC-Code:
12161900
PubChem Substanz-ID:
57648188
NACRES:
NA.25

Beschreibung

anionic

Assay

≥97.0% (dried material, NT)

Form

powder

Optische Aktivität

[α]20/D +36±2°, c = 0.6% in ethanol (dry matter)

Mol-Gew.

micellar avg mol wt 900-1300

Aggregatnummer

2-3

Verlust

≤5% loss on drying

CMC

9-15 mM (20-25°C)

Löslichkeit

H2O: 0.1 M
H2O: 100 mg/mL

HLB

18

SMILES String

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

InChIKey

MUVVIYFKOVLQHL-RCVKHMDESA-M

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Verwandte Kategorien

Allgemeine Beschreibung

Sodium cholate hydrate is a bio-surfactant which can be used as a reducing reagent in aqueous solution.
Sodium cholate hydrate is a non-denaturing, anionic detergent.

Anwendung


  • Optimization in Transdermal Drug Delivery: Applied in the formulation of ultra-elastic nanovesicles, sodium cholate hydrate enhances the bioavailability and anti-inflammatory efficacy of deflazacort, demonstrating its potential in transdermal drug delivery systems, which can be adapted for diagnostic purposes (Ali et al., 2021).

  • Nanocarrier Formulations for IVDs: The study utilizes sodium cholate hydrate in the surface modification of bilosomes, serving as a functional and biocompatible nanocarrier for hybrid compounds, a method applicable to the formulation of innovative IVD reagents (Waglewska et al., 2020).

  • IVD Reagent Formulation for Skin Delivery: Sodium cholate hydrate is featured in the development of nano-transfersomes for the delivery of antioxidants, showcasing its role in creating skin-applied diagnostic reagents that offer antioxidant and anti-aging effects (Avadhani et al., 2017).

  • Sorting and Separation Techniques in Nanotechnology: Demonstrating the affinity-mediated sorting order reversal, sodium cholate hydrate is critical in density gradient ultracentrifugation techniques, highlighting its utility in the precise sorting and preparation of materials for diagnostic assays (Jang et al., 2016).

H-Sätze

H412

P-Sätze

P273 - P501

Gefahreneinstufungen

Aquatic Chronic 3

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Ewelina Waglewska et al.
Nanomaterials (Basel, Switzerland), 10(12) (2020-12-17)
In the present contribution, we demonstrate a new approach for functionalization of colloidal nanomaterial consisting of phosphatidylcholine/cholesterol-based vesicular systems modified by FDA-approved biocompatible components, i.e., sodium cholate hydrate acting as a biosurfactant and Pluronic P123-a symmetric triblock copolymer comprising poly(ethylene
Sonia Biccai et al.
ACS nano, 13(6), 6845-6855 (2019-06-15)
Nanocomposite strain sensors, particularly those consisting of polymer-graphene composites, are increasingly common and are of great interest in the area of wearable sensors. In such sensors, application of strain yields an increase in resistance due to the effect of deformation
Jilite Wang et al.
Bioscience, biotechnology, and biochemistry, 79(3), 456-461 (2014-11-07)
Dietary plant protein is well known to reduce serum cholesterol levels. Rice bran is a by-product of rice milling and is a good source of protein. The present study examined whether feeding rats a high-cholesterol diet containing 10% rice bran
Mayu Kakehi et al.
Toxicological sciences : an official journal of the Society of Toxicology, 147(2), 360-369 (2015-07-17)
There are various interspecies differences in xenobiotic-metabolizing enzymes. It is known that cats show slow glucuronidation of drugs such as acetaminophen and strong side effects due to the UGT1A6 pseudogene. Recently, the UGT1A6 pseudogene was found in the Northern elephant
Yuri Kashima et al.
PloS one, 9(8), e105073-e105073 (2014-08-22)
Royal jelly (RJ) intake lowers serum cholesterol levels in animals and humans, but the active component in RJ that lowers serum cholesterol level and its molecular mechanism are unclear. In this study, we set out to identify the bile acid-binding
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.