BP587

Fluticasonpropionat

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): (6α,11β,16α,17α)-6,9-Difluor-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-dien-17-thiocarbonsäure-S-(fluormethyl)-ester
• Empirische Formel (Hill-System): C₂₅H₃₁F₃O₅S
• CAS-Nummer: 80474-14-2
• Molekulargewicht: 500.57
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00866007

Eigenschaften

• grade: pharmaceutical primary standard
• API family: fluticasone
• form: solid
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
• InChI: 1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
• InChI key: WMWTYOKRWGGJOA-CENSZEJFSA-N
• Gene Information: human ... NR3C1(2908)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fluticasone propionate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Fluticasone and Salmeterol Inhalation Powder

Fluticasone and Salmeterol Inhalation Powder, pre-metered

Fluticasone Nasal Spray

Fluticasone and Salmeterol Pressurised Inhalation, Suspension

Fluticasone Pressurised Inhalation

Fluticasone Nasal Drops

Fluticasone Cream

Fluticasone Inhalation Powder

Fluticasone Ointment

Fluticasone Inhalation Powder, pre-metered

Biochem/physiol Actions

Fluticasonpropionat ist ein Glucocorticoid der zweiten Generation. Es wird als entzündungshemmendes Mittel bei Asthma verwendet. Eine erhöhte konzentrationsabhängige eosinophile Apoptose über den Glucocorticoid-Rezeptor wurde gezeigt.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Warning
• hcodes: H361f,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2 - STOT RE 2
• target_organs: Endocrine system
• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable