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Merck

79266

Supelco

Trimethylphenylammoniumhydroxid -Lösung

~0.5 M (CH3)3N(OH)C6H5 in methanol, for GC derivatization, LiChropur

Synonym(e):

TMAH, Trimethylanilinium-hydroxid

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About This Item

Lineare Formel:
(CH3)3N(OH)C6H5
CAS-Nummer:
Molekulargewicht:
153.22
Beilstein:
3917033
MDL-Nummer:
UNSPSC-Code:
12000000
PubChem Substanz-ID:
NACRES:
NA.22

Qualität

for GC derivatization
LiChropur

Qualitätsniveau

Form

liquid

Eignung der Reaktion

reagent type: derivatization reagent
reaction type: Esterifications

Konzentration

~0.5 M (CH3)3N(OH)C6H5 in methanol

Methode(n)

gas chromatography (GC): suitable

Verunreinigungen

≤0.2% halides (as chloride)

Lagertemp.

2-8°C

SMILES String

[OH-].C[N+](C)(C)c1ccccc1

InChI

1S/C9H14N.H2O/c1-10(2,3)9-7-5-4-6-8-9;/h4-8H,1-3H3;1H2/q+1;/p-1

InChIKey

HADKRTWCOYPCPH-UHFFFAOYSA-M

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Allgemeine Beschreibung

Trimethylphenylammonium hydroxide (TMAH) is a methylating reagent.

Anwendung

Learn more in the Product Information
Suitable for the derivatization of amino acids, n-methyl and n-aryl carbamates and fatty acids, clonidine, and substituted phenylureas.
TMAH may be used as a 0.1 mole/litre solution in methanol to determine plasma concentrations of carbamazepine and other anticonvulsant drugs, including phenobarbital, diphenylhydantoin, primidone, and mephenytoin using Gas-Liquid Chromatography.

Sonstige Hinweise

Kann Verkaufsbeschränkungen unterliegen.
Reagent for n-methyl and methyl esters.

Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 1

Zielorgane

Eyes

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 3

Flammpunkt (°F)

51.8 °F - closed cup

Flammpunkt (°C)

11 °C - closed cup

Persönliche Schutzausrüstung

Faceshields, Gloves, Goggles


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Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
J C Roger et al.
Clinical chemistry, 19(6), 590-592 (1973-06-01)
Y El-Nahhal et al.
Journal of agricultural and food chemistry, 48(10), 4791-4801 (2000-10-29)
This study aimed to design formulations of hydrophobic herbicides, alachlor and metolachlor, by adsorbing them on the clay mineral montmorillonite preadsorbed by the small organic cation phenyltrimethylammonium (PTMA). An adsorption model that considers electrostatics and specific binding and the possibility
Jie Zhang et al.
Journal of chromatography. A, 1216(44), 7527-7532 (2009-04-07)
A method has been established for the determination of four pharmaceutically active compounds (ibuprofen, ketoprofen, naproxen and clofibric acid) in water samples using dynamic hollow fiber liquid-phase microextraction (HF/LPME) followed by gas chromatography (GC) injection port derivatization and GC-mass spectrometric
Alec N Salt et al.
Hearing research, 283(1-2), 14-23 (2011-12-20)
It has been widely believed that drug entry from the middle ear into perilymph occurs primarily via the round window (RW) membrane. Entry into scala vestibuli (SV) was thought to be dominated by local, inter-scala communication between scala tympani (ST)
Alec N Salt et al.
Hearing research, 182(1-2), 24-33 (2003-09-02)
Our understanding of the perilymph kinetics of drugs depends largely on data obtained by the analysis of perilymph samples. Although a number of studies have demonstrated qualitatively that perilymph samples may be contaminated by cerebrospinal fluid (CSF), and some investigations

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