79267

Trimethylphenylammoniumhydroxid -Lösung

~25% in H₂O (1.68 M)

• Synonym(e): TMAH, Trimethylanilinium-hydroxid
• Lineare Formel: (CH₃)₃N(OH)C₆H₅
• CAS-Nummer: 1899-02-1
• Molekulargewicht: 153.22
• UNSPSC Code: 12352005
• NACRES: NA.22
• PubChem Substance ID: 57652783
• MDL number: MFCD00041899
• Beilstein/REAXYS Number: 3917033
• Concentration: ~25% in H₂O (1.68 M)
• Form: liquid

Eigenschaften

• form: liquid
• Quality Segment: 100
• reaction suitability: core: ammonium, reaction type: phase-transfer
• concentration: ~25% in H₂O (1.68 M)
• refractive index: n20/D 1.395
• functional group: amine
• SMILES string: [OH-].C[N+](C)(C)c1ccccc1
• InChI: 1S/C9H14N.H2O/c1-10(2,3)9-7-5-4-6-8-9;/h4-8H,1-3H3;1H2/q+1;/p-1
• InChI key: HADKRTWCOYPCPH-UHFFFAOYSA-M

Beschreibung

General description

Trimethylphenylammonium hydroxide solution (TMPAH) is a quaternary ammonium compound that is commonly used as a strong base in organic synthesis. It is also used as a deprotecting agent for the removal of t-butoxycarbonyl (Boc) groups from amino acids or peptides and benzyl protecting groups from alcohols or amines.

Application

Trimethylphenylammonium hydroxide solution can be used to initiate the polymerization of the monomer 1,8-dihydroxymethyl-1,3,5,7-octatetrayne (DHOT) for the preparation of polymer nanospheres. It is also used as a base in the synthesis of alkyl 3-nitroacrylates via aldol reaction with nitroacetaldehyde or nitroacetone.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• Gefahrencodes: H314
• Sicherheitshinweise: P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Lagerklasse: 8A - Combustible corrosive hazardous materials
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter