Unfortunately, this item is not tested for the suitability of cell culture applications. There is no cell culture-tested product option at this time.
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37095
Staurosporin
VETRANAL®, analytical standard
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 10 mg | Warenkorb auf Verfügbarkeit prüfen | € 1.420,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C28H26N4O3
CAS-Nummer:
Molekulargewicht:
466.53
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Technischer Dienst
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Unterstützung erhaltengrade
analytical standard
Quality Segment
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
SMILES string
CN[C@@H]1C[C@@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35
InChI
1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1
InChI key
HKSZLNNOFSGOKW-ZGQXJOJZSA-N
General description
Staurosporin gehört zur Klasse der Indolcarbazolalkaloide und weist antimykotische und antioomykotische Wirkungen auf. Es wird aus Streptomyces sp. isoliert und ist ein Breitspektruminhibitor von Proteinkinase.
Other Notes
Weitere Informationen zur geeigneten Instrumententechnik finden Sie im Analysenzertifikat des Produkts. Weitere Unterstützung erhalten Sie vom technischen Kundendienst.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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Dieser Artikel | |||
|---|---|---|---|
| grade analytical standard | grade Molecular Biology | grade - | grade - |
| format neat | format - | format - | format - |
| shelf life limited shelf life, expiry date on the label | shelf life - | shelf life - | shelf life - |
| product line VETRANAL® | product line - | product line - | product line - |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - | technique(s) - | technique(s) cell culture | mammalian: suitable |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 2
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Karin Anestål et al.
PloS one, 3(4), e1846-e1846 (2008-04-03)
SecTRAPs (selenium compromised thioredoxin reductase-derived apoptotic proteins) can be formed from the selenoprotein thioredoxin reductase (TrxR) by targeting of its selenocysteine (Sec) residue with electrophiles, or by its removal through C-terminal truncation. SecTRAPs are devoid of thioredoxin reductase activity but
A Gescher
General pharmacology, 31(5), 721-728 (1998-11-11)
1. Protein kinase C (PKC) is a family of serine/threonine-directed protein kinases that are pivotal regulators of cellular growth, transformation and death. PKC has therefore been considered to be a suitable target for novel antineoplastic drugs. 2. Twenty years ago
S Ståhl et al.
Cell death & disease, 4, e454-e454 (2013-01-11)
Radiation therapy is frequently used to treat non-small cell lung cancers (NSCLCs). We have previously shown that a combination of ionizing radiation (IR) and the staurosporine analog PKC 412, but not Ro 31-8220, increases cell death in NSCLC cells. To
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 37095-10MG | 04061834039914 |
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