Fortfahren mit
06689
3-Methyl-glutaconsäure, Mischung aus E- und Z-Isomeren
≥98.0% (HPLC)
Synonym(e):
3-Methyl-2-pentendisäure, NSC 249232
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 250 mg | Warenkorb auf Verfügbarkeit prüfen | € 518,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C6H8O4
CAS-Nummer:
Molekulargewicht:
144.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1722907
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥98.0% (HPLC)
application(s)
clinical testing
format
neat
storage temp.
2-8°C
SMILES string
C/C(CC(O)=O)=C\C(O)=O
InChI
1S/C6H8O4/c1-4(2-5(7)8)3-6(9)10/h2H,3H2,1H3,(H,7,8)(H,9,10)/b4-2+
InChI key
WKRBKYFIJPGYQC-DUXPYHPUSA-N
Biochem/physiol Actions
3-Methylglutaconic acid is a metabolite (as the CoA thioester) in the leucine degradative pathway as well as the mevalonate shunt, a pathway that links isoprenoid metabolism with mitochondrial acetyl-CoA metabolism. 3-Methylglutaconic acid accumulates in patients with a deficiency of 3-methylglutaconyl-CoA hydratase.
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Dieser Artikel | |||
|---|---|---|---|
| format neat | format neat | format - | format - |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| assay ≥98.0% (HPLC) | assay ≥97.0% (HPLC) | assay ≥99.0% (acidimetric) | assay - |
| application(s) clinical testing | application(s) clinical testing | application(s) - | application(s) - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-30°C | storage temp. 2-30°C |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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E Holme et al.
Pediatric research, 32(6), 731-735 (1992-12-01)
We report the finding of mitochondrial ATP-synthase deficiency in a child with persistent 3-methylglutaconic aciduria. The child presented in the neonatal period with severe lactic acidosis, which was controlled by Na-HCO3 and glucose infusions. During the 1st y of life
R I Kelley
Clinica chimica acta; international journal of clinical chemistry, 220(2), 157-164 (1993-11-15)
A method is described for quantification of the trace metabolite, 3-methylglutaconic acid, by isotope-dilution gas chromatography/mass spectrometry using synthetic 3-[2,4,6-13C3]methylglutaconic acid. Results are shown for quantification of 3-methylglutaconic acid in plasma, urine, cerebrospinal fluid and amniotic fluid for both normal
H Costeff et al.
Annals of neurology, 33(1), 103-104 (1993-01-01)
Behr's syndrome consists of recessively inherited infantile optic atrophy, together with chronic neurological disturbances such as ataxia, extrapyramidal dysfunction, and juvenile spastic paresis. This syndrome was found to be relatively common among Iraqi Jews. For our study, 18 such patients
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 8034560250 | 04022536380988 |
| 8034561000 | 04022536380995 |
| 290734-100ML | 04061826303597 |
| D27802-100G | 04061835253142 |
| 290734-500ML | 04061826303603 |
| 8034560100 | 04022536380971 |
| D27802-25G | 04061833562550 |
| D27802-500G | 04061833562574 |
| D27802-2KG | 04061833562567 |
| 06689-250MG | 04061833471609 |
| 06689-50MG | 04061833414774 |