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Chymostatin

lyophilized powder, protease inhibitor, Chemicon®

Synonym(e):

Protease Inhibitor

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Über diesen Artikel

UNSPSC Code:
51111800
NACRES:
NA.77
eCl@ss:
32160405
Quality level:
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
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Produktname

Chymostatin,

manufacturer/tradename

Chemicon®

Quality Level

shipped in

dry ice

General description

Chymostatin. M.W. 604.92

Mixture of types A, B and C. Inhibits Chymotrypsin-like serine proteases including alpha, beta, gamma and delta chymotrtrypsins.

Sequence:

[(S)-1-Carboxy-2-Phenylethyl]-Carbamoyl-a-[2-Iminohexahydro-4(S)-Pyrimidyl]-(S)-Glycyl-X-Phenylalaninal

X: L-Leu (type A), L-Ile (type B), L-Val (type C)

Working concentrations 10-100μM.

Stable for several hours. Soluble in DMSO and glacial acetic acid. Solutions are stable for a month at -20ºC.

5mg/825 microliters in DMSO = 10mM solution.

Dilute 1:100 for 100μM working solution.

Biochem/physiol Actions

Inhibitor Type: Protease Inhibitors

Physical form

Lyophilized. Dissolve in dimethylsulfoxide (DMSO). After powder is thoroughly dissolved, dilute the DMSO solution with 0.9% NaCl. The concentration of DMSO should be maintained at 10% or higher. Otherwise chymostatin may precipitate from the solution.



Example: Reconstitute 1 mg of chymostatin with 1.65 mL of DMSO. Then add 14.85 mL of 0.9% NaCl. This furnishes a 10-4 M solution. No preservatives added.

Preparation Note

Maintain lyophilized material at -20ºC for up to one year. Store reconstituted product in aliquots at -20ºC for up to 3-4 weeks. Do not thaw and refreeze.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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23079011004638001C7268
manufacturer/tradename

Chemicon®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Roche

manufacturer/tradename

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

300

shipped in

dry ice

shipped in

ambient

shipped in

-

shipped in

-


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes.
H Umezawa et al.
The Journal of antibiotics, 23(8), 425-427 (1970-08-01)



Global Trade Item Number

SKUGTIN
EI604053252619915

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